SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

PURPOSE: The pharmacology, pharmacokinetics, and clinical trials of and drug interactions and formulary considerations associated with atazanavir, the newest protease inhibitor (PI) to treat human immunodeficiency virus (HIV) infection, are...

Recent evidence suggests that transmission of human immunodeficiency virus (HIV) is increasing among late middle-aged and older adults (50 years of age or older). However, research studies explaining the unique...

In order to determine the changes in the human immunodeficiency virus type-1 (HIV-1) envelope that corresponds with disease progression, a meta-analysis of viral forms was performed using HIV-1 sequences obtained...

BACKGROUND AND PURPOSE: Adolescent girls now represent one of the fastest growing groups of persons infected with HIV. A systematic review was undertaken to identify and critique the most scientifically...

PURPOSE: A successful prophylactic HIV vaccine will probably require neutralizing antibodies and vigorous CTL (CD8+ T-cytotoxic lymphocyte) responses. Canarypox vector-based HIV vaccines (ALVAC-HIV) have been gaining momentum as promising HIV...

OBJECTIVE: To summarize studies that have tested the efficacy of human immunodeficiency virus (HIV) sexual risk-reduction interventions in adolescents. DATA SOURCES: Reports were gathered from computerized databases, by contacting individual...

XST: This is a critical abstract of a systematic review that meets the criteria for inclusion on DARE. Each critical abstract contains a brief summary of the review methods, results...

Objective: To evaluate the efficacy and safety of simplified maintenance therapy (SMT) compared with continued protease inhibitor (PI) therapy. Design: Meta-analysis of nine randomized controlled trials in which 833 patients...

Due to advanced antiretroviral treatments, persons with HIV/AIDS (PWH/As) live longer and experience various physical and cognitive impairments during the course of their disease. Often, informal caregivers assist PWH/As to...

BACKGROUND: MSM remain at great risk for HIV infection. Program planners and policy makers need descriptions of interventions and quantitative estimates of intervention effects to make informed decisions concerning prevention...

BACKGROUND: The prevention and early treatment of infections are the mainstay of the medical management of the majority of people with HIV infection, who live in low income countries without...

OBJECTIVE: To review the methods and findings of studies that assess the costs and consequences of interventions to reduce mother-to-child HIV transmission in sub-Saharan Africa. DESIGN: Systematic literature review. METHODS:...