SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Population pharmacokinetic meta-analysis with efavirenz

2002

A population-based pharmaco-kinetic (PK) model has been developed for efavirenz based on 16 phase I studies. The combined data set consisted of 334 healthy volunteers, 2,907 efavirenz dose administrations and...

Nonoxynol-9 spermicide for prevention of vaginally acquired HIV and other sexually transmitted infections: Systematic review and meta-analysis of randomised controlled trials including more than 5000 women

2002

We aimed to determine the effectiveness of the vaginally administered spermicide nonoxynol-9 (N-9) among women for the prevention of HIV and other sexually transmitted infections (STIs). We did a systematic...

Review and meta-analysis of HIV prevention intervention research for heterosexual adult populations in the United States

2002

A meta-analysis was performed to examine the effects of 14 behavioral and social interventions for heterosexual adults on their adoption of safer sex behaviors or incidence of sexually transmitted diseases...

Does patient sex affect human immunodeficiency virus levels?

2002

We undertook a critical epidemiological review of the available evidence concerning whether women have lower levels of human immunodeficiency virus (HIV) RNA than do men at similar stages of HIV...

A systematic review of the management of oral candidiasis associated with HIV/AIDS

2002

The purpose of this review was to investigate the management of oral candidiasis in HIV/AIDS patients and to evaluate the different guidelines available for its management. A number of topical...

Vaginal disinfection during labour for reducing the risk of mother-to-child transmission of HIV infection

2002

BACKGROUND: Mother-to-child transmission (MTCT) of HIV infection is one of the most tragic consequences of the HIV epidemic, especially in resource-limited countries, resulting in about 650 000 new paediatric HIV...

Management of chronic hepatitis C

2002

Objectives: Hepatitis C is the most common blood-borne infection in the United States and can lead to serious complications including cirrhosis and hepatocellular carcinoma (HCC). The objectives of this report...

A meta-analysis of the neuropsychological sequelae of HIV infection

2002

This meta-analysis summarizes the broad spectrum of neuropsychological research on HIV disease across a sample of 41 primary studies and an aggregate of 8,616 participants for 10 major neuropsychological ability...

Child-rearing practices of primary caregivers of HIV-infected children: An integrative review of the literature

2002

The number of human immunodeficiency virus (HIV)-infected children has increased because of the HIV and acquired immunodeficiency syndrome epidemic. Yet little is known about the child-rearing practices of these children’s...

Risk of human immunodeficiency virus infection in herpes simplex virus type 2-seropositive persons: A meta-analysis

2002

To determine the contribution of herpes simplex type 2 (HSV-2) infection to the risk of human immunodeficiency virus (HIV) acquisition, a systematic review of literature and data synthesis were done....

Nystatin prophylaxis and treatment in severely immunodepressed patients

2002

BACKGROUND: Nystatin is sometimes used prophylactically in patients with severe immunodeficiency or in the treatment of fungal infection in such patients, although the effect seems to be equivocal. OBJECTIVES: To...

Preventing HIV/AIDS risk behavior among youth

2002

The purpose of this article is to evaluate the quality of published studies conducted in North America that assessed behavior change interventions to prevent HIV/AIDS among people ages 12-24 years....

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