SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Systematic review and meta-analysis of evidence for increasing numbers of drugs in antiretroviral combination therapy

2002

Objective. To assess the evidence for the effectiveness of increasing numbers of drugs in antiretroviral combination therapy. Design. Systematic review, meta-analysis, and meta-regression of fully reported randomised controlled trials. All...

Meta-analysis of diagnostic procedures for Pneumocystis carinii pneumonia in HIV-1-infected patients

2002

Sputum induction is a simple and noninvasive procedure for Pneumocystis carinii pneumonia (PCP) diagnosis in human immunodeficiency virus-1-positive patients, although less sensitive than bronchoalveolar lavage (BAL). In order to obtain...

Vaginal disinfection during labour for reducing the risk of mother-to-child transmission of HIV infection

2002

BACKGROUND: Mother-to-child transmission (MTCT) of HIV infection is one of the most tragic consequences of the HIV epidemic, especially in resource-limited countries, resulting in about 650 000 new paediatric HIV...

Women, sex, and HIV: social and contextual factors, meta-analysis of published interventions, and implications for practice and research

2002

This article is focused on examining social and contextual factors related to HIV-risk behavior for women. Specifically, this article has three main purposes: to review the literature on selected social...

Nystatin prophylaxis and treatment in severely immunodepressed patients

2002

BACKGROUND: Nystatin is sometimes used prophylactically in patients with severe immunodeficiency or in the treatment of fungal infection in such patients, although the effect seems to be equivocal. OBJECTIVES: To...

Gender difference in HIV RNA levels: A meta-analysis of published studies

2002

Plasma HIV RNA copy number is a strong prognostic marker of progression to AIDS in antiretroviral-naive persons. Recent research suggests women have lower HIV RNA levels than comparable men. Because...

Nonoxynol-9 for preventing vaginal acquisition of sexually transmitted infections by women from men

2002

BACKGROUND: The incidence and prevalence of sexually transmitted infections (STI) and other reproductive tract infections (RTI) is high in much of the developing and parts of the developed worlds. STIs...

Population pharmacokinetic meta-analysis with efavirenz

2002

A population-based pharmaco-kinetic (PK) model has been developed for efavirenz based on 16 phase I studies. The combined data set consisted of 334 healthy volunteers, 2,907 efavirenz dose administrations and...

Effective approaches to reducing adolescent unprotected sex, pregnancy, and childbearing

2002

In the United States, there exist a multitude of different approaches to reducing adolescent sexual risk-taking, unintended pregnancy, childbearing, and sexually transmitted disease, including HIV. While many of these approaches...

A meta-analysis of the neuropsychological sequelae of HIV infection

2002

This meta-analysis summarizes the broad spectrum of neuropsychological research on HIV disease across a sample of 41 primary studies and an aggregate of 8,616 participants for 10 major neuropsychological ability...

Preventing HIV/AIDS risk behavior among youth

2002

The purpose of this article is to evaluate the quality of published studies conducted in North America that assessed behavior change interventions to prevent HIV/AIDS among people ages 12-24 years....

A systematic review of the management of oral candidiasis associated with HIV/AIDS

2002

The purpose of this review was to investigate the management of oral candidiasis in HIV/AIDS patients and to evaluate the different guidelines available for its management. A number of topical...

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