SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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HIV-1 drug resistance in children and implications for pediatric treatment strategies: A systematic review and meta-analysis

2025

Introduction Failure in the prevention of mother-to-child HIV transmission (PMTCT) and pediatric treatment challenges led to pretreatment drug resistance (PDR) and acquired drug resistance (ADR) in children with HIV (CWHIV)....

Barriers to retention in care among adults with HIV in developed countries: An integrative review

2025

Focusing on factors hindering viral suppression is essential for improving the health outcomes of people with Human Immunodeficiency Virus (HIV) and working towards ending the HIV/AIDS epidemic. The aim of...

Use of behavior change techniques in digital HIV prevention programs for adolescents and young people: Systematic review

2025

BACKGROUND: HIV infections have caused severe public health and economic burdens to the world. Adolescents and young people continue to constitute a large proportion of newly diagnosed HIV cases. Digital...

Prevalence of suicidal ideation, suicide attempts and suicide deaths in people living with HIV: Are there differences between geographic locations or sexes? : An overview of systematic reviews with meta-analysis

2025

BACKGROUND: Preventing suicide is an important clinical and research priority according to the World Health Organization across lifespan. OBJECTIVE: This study summarizes the prevalence of suicidal ideation, attempts, and suicide...

The global prevalence of an factors associated with parasitic coinfection in people living with viruses: A systematic review and meta-analysis

2025

Coinfection with parasites and viruses can exacerbate disease transmission, outcomes and therapy. This study searched the Web of Science, PubMed, Scopus and JSTOR databases for publications on the prevalence of...

Cost-effectiveness of HIV prevention strategies: A systematic review of economic evaluations

2025

BACKGROUND: HIV/AIDS continues to pose a significant global health challenge, especially in low- and middle-income countries. Economic evaluations are essential to identify cost-effective prevention strategies and allocate limited healthcare resources...

Determinants of HIV related mortality in African children on antiretroviral therapy: Clinical and immunological insights from a systematic review and meta-analysis

2025

BACKGROUND: The HIV epidemic in Africa is still a serious public health concern, particularly for children who are more vulnerable to its negative consequences. Various studies carried out in different...

Dolutegravir + lamivudine effectiveness and tolerability in real-world cohorts with HIV-1 across Asia and South America: A systematic literature review

2025

Background: Dolutegravir (DTG) + lamivudine (3TC) has demonstrated efficacy and safety in phase 3 clinical trials; however, most published data are from people with HIV-1 in North America and Europe. Methods: To...

Influences of gender-based stigma on HIV prevention and care among older women: A scoping review

2025

Older women living with HIV are uniquely situated at multiple marginalized intersections because of their gender, age, and HIV status. However, research into how gender-based stigma (GBS) affects HIV prevention...

PrEP delivery for US adolescents and young adults: A systematic review and narrative synthesis

2025

Despite proven efficacy in preventing human immunodeficiency virus (HIV) transmission, pre-exposure prophylaxis (PrEP) remains underutilized among adolescents and young adults (AYA) in the United States (US). This systematic review and...

Marriage and Steady Relationships with Women in Men Who Have Sex with Men in Sub-Saharan Africa: A Mixed-Method Systematic Review and Meta-analyses

2025

High HIV prevalence in Sub-Saharan African (SSA) in men who have sex with men (MSM) leads to greater risk for their wives and other steady female partners because of prolonged...

Global human immunodeficiency virus prevalence and risk behaviors in transmasculine Individuals: A scoping review

2025

PURPOSE: This scoping review sought to synthesize human immunodeficiency virus (HIV) and sexually transmitted infection (STI) prevalence, incidence, risk behaviors, and risk perceptions among transmasculine (TM) individuals globally. METHODS: Eligible...

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