SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Machine learning for personalized risk assessment of HIV, syphilis, gonorrhoea and chlamydia: A systematic review and meta-analysis

2025

Background Machine learning (ML) shows promise for sexually transmitted infection (STI) risk prediction, but systematic evidence of its effectiveness remains fragmented. Methods We systematically searched six electronic databases, three preprint...

Aetiology of fever of unknown origin in people living with HIV: A systematic review and meta-analysis

2025

Introduction: Fever of unknown origin (FUO) in people living with HIV presents a significant diagnostic challenge due to its broad range of potential aetiologies. Objective: The aims of this study were to...

Cost-effectiveness of HIV prevention interventions in sub-Saharan Africa (2019-2025): A systematic review

2025

INTRODUCTION: This systematic review synthesizes recent evidence on the cost-effectiveness of HIV prevention interventions in sub-Saharan Africa (SSA), where over 70% of the global HIV burden resides. METHODS: Following PRISMA...

Mobile health intervention tools promoting HIV pre-exposure prophylaxis among adolescent girls and young women in sub-Saharan Africa: Scoping review

2025

BACKGROUND: In 2022, 3100 adolescent girls and young women in sub-Saharan Africa experienced new HIV infections each week. HIV pre-exposure prophylaxis (PrEP) is effective at preventing HIV but has limited...

Antifungal resistance of Candida spp. isolates from HIV/AIDS patients in Iran 1999–2024: A systematic review and meta-analysis

2025

Background Antifungal resistance in Candida species in HIV/AIDS patients due to the scarcity of antifungal agents is important particularly in Iran with an estimate of 46,000 individuals living with HIV. This systematic...

A scoping review of grey zone use for transfusion-transmitted infection screening among blood donors

2025

BACKGROUND AND OBJECTIVES: Screening for transfusion-transmitted infections (TTIs) among blood donors is done using qualitative screening assays. Screening values that are close to cut-off values lie in the uncertainty zone,...

Cardiovascular disease and its risk factors among people living with HIV: A systematic review and meta-analysis

2025

This meta-analysis aimed to quantify the latest cardiovascular disease (CVD) incidence rate and assess the impact of risk factors among people living with HIV (PLWH). We searched PubMed, Embase, Web...

Global prevalence of advanced HIV disease in healthcare settings: A rapid review

2025

Introduction Recent studies have indicated a high enduring burden of advanced HIV disease, but estimates across regions and settings are lacking. The aim of this study was to estimate the...

The burden of HPV infections and HPV-related diseases among people with HIV: A systematic literature review

2025

Human papillomavirus (HPV) is associated with a significant global burden of precancerous lesions and cancer. People with HIV (PWH) are at higher risk of HPV infection and HPV‐related diseases. This...

Adherence definitions, measurement modalities, and psychometric properties in HIV, diabetes, and nutritional supplementation studies: A scoping review

2025

Measuring adherence has been a priority for researchers to help inform effective care for patients regularly consuming medications for chronic conditions. As a widely accepted “gold standard” adherence measure or...

What has been studied about attitudes and social stigma towards HIV/AIDS? A global bibliometric study with correlations on global health HIV-related indicators

2025

Introduction: This study aimed to assess, through health metrics and bibliometric analysis, the global research on attitudes and social stigma of people living with HIV/AIDS and to identify research findings,...

The diagnostic significance of the C-reactive protein (CRP) in HIV/TB coinfection: A systematic review and meta-analysis

2025

Background Drug-resistant Mycobacterium tuberculosis strains have challenged efforts to combat tuberculosis (TB), a major global killer. C-reactive protein (CRP) shows promise as a biomarker for TB screening, particularly in HIV-positive...

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