SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Antibiotics for syphilis diagnosed during pregnancy

2001

Background: Congenital syphilis is an increasing problem particularly in many developing countries and in the transitional economies of Eastern Europe and the former Soviet Union. In several countries this increase...

A comparative meta-analysis on the variability in test performance among FDA-licensed enzyme immunosorbent assays for HIV antibody testing

2001

Background. Although independently published studies have compared diagnostic test performance among various manufactured enzyme immunosorbent assays (EIAs) used in HIV antibody testing, none have attempted to formally synthesize such results...

A systematic review of the epidemiologic interactions between classic sexually transmitted diseases and HIV: How much really is known?

2001

BACKGROUND: Many studies have explored the role of “classic” sexually transmitted diseases (STDs) in determining the pattern of HIV epidemics. However, the many different STDs may contribute in different ways,...

Nevirapine or efavirenz combined with two nucleoside reverse transcriptase inhibitors compared to HAART: A meta-analysis of randomized clinical trials

2001

Purpose: A meta-analysis of randomized controlled trials (RCTs) was performed to evaluate effectiveness and tolerability of triple antiretroviral therapy regimens in HIV-infected patients. Method: RCTs including the nonnucleoside reverse transcriptase...

Meta-analysis of the relationship between HIV infection and risk for depressive disorders

2001

Objective: Each of 10 published studies investigating the relationship between HIV infection and risk for depressive disorders concluded that HIV-positive individuais are at no greater risk for depression than comparable...

Structured treatment interruptions for the management of HIV infection

2001

Antiretroviral drugs constitute a milestone in the treatment of human immunodeficiency virus (HIV) infection; however, emerging problems limit their long-term use, and an increasing number of patients interrupt the prescribed...

Use of cidofovir in progressive multifocal leukoencephalopathy

2001

BACKGROUND: Progressive multifocal leukoencephalopathy (PML) is a subacute demyelinating illness caused by the JC virus, a polyomavirus that occurs in 4-5% of HIV-positive patients. Mortality is high, and no useful...

Systematic review of combination antiretroviral therapy with didanosine plus hydroxyurea: A partial solution to Africa’s HIV/AIDS problem?

2001

Effective antiretroviral therapy remains beyond the reach of most human immunodeficiency virus (HIV)-infected persons living in the third world because of its tremendous cost. The cancer drug, hydroxyurea, inhibits HIV-1...

Role of therapeutic drug monitoring for protease inhibitors

2001

OBJECTIVE: To review the role of therapeutic drug monitoring (TDM) for protease inhibitors in the treatment of HIV infection. DATA SOURCES: Primary articles were identified using MEDLINE (1966-October 2000), EMBASE...

Primary pulmonary hypertension in HIV patients: A systematic review

2001

The relationship between grade of pulmonary hypertension and factors associated with human immunodeficiency virus among patients with HIV infection is poorly documented. This report documents the most extensive attempt made...

Management of dental patients who are HIV-positive: Antifungal treatments

2001

This is the second in a series of systematic reviews of critical oral health care issues collaboratively supported by the National Institute of Dental and Craniofacial Research (NIDCR) and the...

Anal intraepithelial neoplasia in HIV positive people

2001

OBJECTIVE: To review the current literature on HIV associated anal intraepithelial neoplasia (AIN). METHODS: A comprehensive Medline/Pubmed search was performed for the years 1980-2001 (January) for articles pertaining to HIV...

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