SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Family influences on antiretroviral therapy adherence in youth with HIV in the United States: A systematic review

2025

HIV poses a significant issue in the United States and understanding how HIV-positive populations adhere to treatments, specifically with antiretroviral therapy (ART), is vital for researchers to find approaches to...

Reporting and handling of missing data in published studies of co-morbid hypertension and diabetes among people living with HIV/AIDS: A systematic review

2025

BACKGROUND: As hypertension and diabetes emerge as co-morbidities among people living with HIV/AIDS (PLWH), the need for robust epidemiological research to inform policy and action is imperative. Proper reporting and...

Cabotegravir plus rilpivirine injection for virally suppressed persons with HIV-1 infection: A systematic review and meta-analysis of randomized controlled trials

2025

Purpose: This study evaluated the efficacy and safety of cabotegravir/rilpivirine long-acting formulation compared to oral standard of care at 48 and 52 weeks. Method: We conducted an electronic search (2005-2024) across databases...

The global prevalence of an factors associated with parasitic coinfection in people living with viruses: A systematic review and meta-analysis

2025

Coinfection with parasites and viruses can exacerbate disease transmission, outcomes and therapy. This study searched the Web of Science, PubMed, Scopus and JSTOR databases for publications on the prevalence of...

Network meta-analytical investigations of the performance of HIV combination prevention strategies for Indigenous populations

2025

BACKGROUND: Indigenous populations worldwide face a disproportionate burden of HIV due to structural inequities, cultural marginalization, and limited access to health services. Despite growing recognition of the need for culturally...

The magnitude and patterns of acquired drug resistanace mutations and circulating HIV-1 subtypes in HIV patients in Tanzania, a systematic review and meta-analysis

2025

The emergence and spread of HIV drug resistance mutations (DRMs) pose a threat to current and future treatment options. To inform policy, this review aimed to determine the magnitude and...

Strategies for improving linkage to HIV care after hospital discharge among adults living with HIV in low- and middle-income countries: A systematic review

2025

Purpose Despite the availability of antiretroviral therapy (ART), nearly a quarter of people living with HIV (PLHIV) die within six months after hospital discharge due to complications from AIDS-related illnesses....

FujiLAM assays for tuberculosis detection in people with HIV: A systematic review and meta-analysis

2025

Background There is a global need for a rapid, accurate, and non-sputum point-of-care (PoC) assay for tuberculosis (TB), especially for people with HIV (PLHIV). The Fujifilm SILVAMP TB LAM (FujiLAM),...

Human milk oligosaccharides, microbiome, antiretroviral therapy and HIV infected mothers: Reasons to still promote breastfeeding in HIV context of lactating countries, a mini-narrative review

2025

Breastfeeding is the preferred feeding for newborns during the first 6 months of life and until the age of 2 years or beyond. The benefits of breastfeeding remain significant, even in cases...

Polypharmacy in HIV: Rethinking what counts and why it matters

2025

Polypharmacy, the concurrent use of multiple medications, presents a growing challenge in HIV care as people living with HIV age and experience earlier onset of age-related co-morbidities. However, how polypharmacy...

Racism, homophobia, and the sexual health of young Black men who have sex with men in the United States: A systematic review

2025

Black gay, bisexual, and other men who have sex with men (BMSM) experience the highest rates of HIV acquisition annually out of any population in the United States, and young...

Multidrug resistance tuberculosis in the context of co-infection in Ethiopia: A systematic review and meta-analysis

2025

The rise of multidrug-resistant tuberculosis (MDR-TB) remains a critical public health challenge, particularly in developing countries like Ethiopia. This systematic review and meta-analysis aimed to estimate the pooled prevalence of...

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