SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Acceptability, needs, concerns, and barriers to digital-based interventions for the prevention of mother-to-child transmission of HIV: Systematic review and qualitative meta-aggregation

2025

BACKGROUND: Digital-based interventions have the potential to support initiatives for the prevention of mother-to-child HIV transmission (PMTCT). Nevertheless, reviews to explore experiences and perspectives toward digital-based interventions in mothers living...

High prevalence of baseline Non-R5 viral tropism in PLWH is associated with immune damage: A systematic review and meta-analysis

2025

Objective This systematic review and meta-analysis aims to characterize the distribution of HIV-1 viral tropism at diagnosis among people living with HIV (PLWH) and examine its association with baseline CD4+ T...

An integrative review of PrEP promotion strategies at historically Black colleges and universities to reduce HIV disparities

2025

PURPOSE OF REVIEW: We searched PubMed, CINAHL Plus, Embase, Scopus, Web of Science, and ERIC to identify peer-reviewed studies published between 2015 and 2025 that discussed PrEP at HBCUs. We...

Global prevalence of depressive symptoms among people living with HIV/AIDS: A systematic review and meta-analysis of the past five years

2024

A clear and accurate assessment of depressive symptoms among people living with HIV/AIDS (PLWHA) in the past five years is essential to help develop reasonable and sound interventions to improve...

The cost-effectiveness of Dolutegravir in combination with Tenofovir and Lamivudine for HIV therapy: A systematic review

2024

The World Health Organization (WHO) recommends dolutegravir (DTG), a human immunodeficiency virus (HIV) medicine, as the first- and second-line treatment for all populations because, when compared to an efavirenz (EFV)...

Advancing adolescent and young adult HIV prevention and care and treatment through use of multi-level theories and frameworks: A scoping review and adapted HIV ecological framework

2024

While multi-level theories and frameworks have become a cornerstone in broader efforts to address HIV inequities, little is known regarding their application in adolescent and young adult (AYA) HIV research....

Suicidal ideation, attempt, and its associated factors among adult HIV/AIDS patients in Ethiopia: A systematic review and meta-analysis study

2024

BACKGROUND: WHO statistics show that someone attempts suicide every three seconds and commits suicide every 40 seconds somewhere in the world. There is a scarcity of aggregate evidence in Ethiopia....

A systematic review and meta-analysis of HIV transmission risk behaviors, genetic variations, and antiretroviral (ARV) resistance in LGBT populations

2024

Background: Currently, human immunodeficiency virus and acquired immunodeficiency syndrome (HIV/AIDS) has become one of the major health problems worldwide, including Indonesia. East Java is one of the provinces in Indonesia...

Prevalence and factors associated with viral non-suppression in people living with HIV receiving antiretroviral therapy in sub-Saharan Africa: A systematic review and meta-analysis

2024

Despite advances in HIV treatment, the burden of viral non-suppression (VNS) remains a treatment success concern, particularly in Sub-Saharan African (SSA) countries. We determined the prevalence and factors associated with...

Health-related physical fitness evaluation in HIV-diagnosed children and adolescents: A scoping review

2024

BACKGROUND: Health-related physical fitness has been widely used to investigate the adverse effects of HIV infection/ART in children and adolescents. However, methods/protocols and cut-points applied for investigating health-related physical fitness...

Systematic review and meta-analysis on the effect of depression on ART adherence among women living with HIV

2024

BACKGROUND: Depression is a very common psychiatric disorder in worldwide. Globally, Human Immunodeficiency Virus (HIV) is highly prevalent among women, and are disproportionately affected by depression. Antiretroviral Therapy (ART) adherence...

Impact of HIV coinfection on tuberculosis treatment outcomes in Ethiopia: A systematic review and meta-analysis

2024

Objectives: Despite the implementation of a short-term direct observation treatment programme, HIV coinfection is one of the main determinants of tuberculosis (TB) treatment success. This meta-analysis was conducted to report the...

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