SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Drug-drug interactions potential with the HIV-1 capsid inhibitor lenacapavir

2024

INTRODUCTION: Lenacapavir is the first HIV-1 capsid inhibitor administered subcutaneously twice yearly. While lenacapavir is currently only indicated as salvage therapy, it has the potential to become a foundation of...

Managing low-level HIV viraemia in antiretroviral therapy: a systematic review and meta-analysis

2024

OBJECTIVE: HIV-1 management has advanced significantly with antiretroviral therapy (ART), yet challenges persist, including low-level HIV-1 viraemia (LLV). LLV presents a complex scenario, with varied definitions in the literature, reflecting...

Syndemic theory and its use in developing health interventions and programming: A scoping review

2024

PURPOSE OF REVIEW: The central tenet of syndemics theory is that disease interactions are driven by social factors, and that these factors have to be understood in order to reduce...

A systematic review and meta-analysis of maternal weight changes and pregnancy outcomes associated with integrase inhibitors and tenofovir alafenamide in pregnant women with HIV

2024

OBJECTIVE: The global epidemiology of HIV during pregnancy highlights the challenges faced by women living with HIV worldwide. In 2022, more than 1.3 million pregnant women were living with HIV...

Uptake and acceptability of HIV self-testing among pregnant and postpartum women and their male partners in sub-Saharan Africa: Benefits, challenges, and delivery strategies

2024

BACKGROUND: HIV self-testing (HIVST) offers a novel solution for increasing HIV testing among pregnant and postpartum women and their male partners, especially in low-resource settings. These groups often face barriers...

Skin cancer in patients who are co-infected with HIV/ HBV or HIV/HCV: A systematic review

2024

Skin cancer, the most common cancer in the United States, has been well-described in the literature to be associated with environmental factors including ultraviolet (UV) radiation. However, the effect of...

Interventions supporting engagement with sexual healthcare among people of Black ethnicity: A systematic review of behaviour change techniques

2024

BACKGROUND: Black ethnic groups are disproportionately affected by sexually transmitted infections (STIs). This review aimed to identify interventions designed to increase engagement with sexual healthcare among people of Black ethnicity...

Prevalence of ocular toxoplasmosis among people living with HIV: A systematic review and meta-analysis

2024

Aim: To determine the prevalence of ocular toxoplasmosis among people living with HIV through a systematic review and meta-analysis. Materials & methods: A literature search was conducted, estimating pooled prevalence...

High-sensitivity C-reactive protein among people living with HIV on highly active antiretroviral therapy: A systemic review and meta-analysis

2024

The pathological consequences of inflammation persist in people living with the human immunodeficiency virus (PLWH), regardless of the positive outcomes of highly active antiretroviral therapy (HAART). The current systematic review...

Exploring the experiences of peer support participation for HIV peer volunteers: A meta-synthesis of qualitative research

2024

BACKGROUND: Gaining insights and feedback from HIV peer volunteers about their peer support practice is crucial for optimizing and enhancing the effectiveness and sustainability of peer support for people with...

The impact of social determinants of health on outcomes among individuals with HIV and heart failure: A literature review

2024

This narrative review examines the complex interplay between social determinants of health (SDoH) and the outcomes for individuals living with human immunodeficiency virus (HIV) and heart failure (HF), two conditions...

Digital strategies supporting social network approaches to HIV testing: A scoping review

2024

Purpose of review: This review captured how digital strategies support social network approaches to promote HIV testing. Recent finding: Overall, 29 studies were identified by searching PubMed and Embase for studies published...

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