SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Best practices to increase engagement and retention in hepatitis C care among people who use drugs

2023

Key take-home messages

Cost-effectiveness of anti-retroviral adherence interventions for people living with HIV: A systematic review of decision analytical models

2023

BACKGROUND: Although safe and effective anti-retrovirals (ARVs) are readily available, non-adherence to ARVs is highly prevalent among people living with human immunodeficiency virus/acquired immunodeficiency syndrome (PLWHA). Different adherence-improving interventions have...

The effect of HIV prevalence, CD4 counts and disease severity on the outcome of total knee arthroplasty for haemophilic arthropathy: A systematic review and meta-analysis

2023

Purpose: End-stage knee arthropathy is a recognised complication of haemophilia. It is often treated by total knee arthroplasty (TKA), which is more technically challenging in patients with haemophilia (PwH). It remains...

Global type-specific genital human papillomavirus prevalence in men, by sexual orientation: A systematic review and meta-analysis

2023

BACKGROUND: Knowledge on genital type-specific human papillomavirus (HPV) prevalence among men is important for prevention of HPV-related cancers and other diseases. Men who have sex with men (MSM) have higher...

Interventions to enhance healthcare utilisation among pregnant women to reduce maternal mortality in low- and middle-income countries: a review of systematic reviews

2023

BACKGROUND: Maternal mortality in low- and middle-income countries (LMIC) has reduced considerably over the past three decades, but it remains high. Effective interventions are available, but their uptake and coverage...

Integration of female genital schistosomiasis into HIV/sexual and reproductive health and rights and neglected tropical diseases programmes and services: A scoping review

2023

Female genital schistosomiasis (FGS) affects approximately 56 million women and girls across sub-Saharan Africa and is associated with up to a threefold increased prevalence of HIV. Integrating FGS with HIV...

HIV, hepatitis B & C in people who inject drugs in India: A systematic review of regional heterogeneity & overview of opioid substitution treatment

2023

BACKGROUND OBJECTIVES: This systematic review evaluates the human immunodeficiency virus (HIV), hepatitis C virus (HCV) and hepatitis B virus (HBV) burden among people who inject drugs (PWIDs) in India. In...

Systematic review of neighborhood factors impacting HIV care continuum participation in the United States

2023

Social determinants have been increasingly implicated in accelerating HIV vulnerability, particularly for disenfranchised communities. Among these determinants, neighborhood factors play an important role in undermining HIV prevention. However, there has...

The influence between C-C chemokine receptor 5 (CCR5) genetic polymorphisms and the type-1 human immunodeficiency virus (HIV-1): A 20 years review

2023

Acquired Immune Deficiency Syndrome (AIDS) is an infectious disease caused by the types 1 and 2 Human Immunodeficiency Virus (HIV-1 and HIV-2). Clinical outcomes in patients are highly varied and...

Mapping the effectiveness of integrating mental health in HIV programs: A scoping review

2023

INTRODUCTION: Mental health and substance abuse issues are increasing among HIV-positive people, and it negatively impacts health outcomes like engagement, retention in HIV care, and adherence to ART. Thus, national...

Nutritional status and its determinants among adolescents with HIV on anti-retroviral treatment in low- and middle-income countries: A systematic review and meta-analysis

2023

Purpose This review aimed to determine what methods are used to assess nutritional status, the levels of nutritional status, determinants of undernutrition, and nutritional interventions employed for adolescents with HIV...

Examining the relationship between HIV-related stigma and the health and wellbeing of children and adolescents living with HIV: A systematic review

2023

Human immunodeficiency virus (HIV) affects millions of people globally. The associated stigma remains a challenge for individuals living with HIV and children and adolescents face the additional challenge of withstanding...

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