SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Prevalence and risk factors of cardiovascular disease among people living with HIV in the Asia-Pacific region: A systematic review

2023

BACKGROUND: Cardiovascular diseases (CVD) due to atherosclerosis have become one of the major causes of death among people living with HIV (PLHIV) since effective antiretroviral therapy (ART) has been available...

Performances of Dried Blood Spots and Point-of-Care Devices to Identify Virological Failure in HIV-Infected Patients: A Systematic Review and Meta-Analysis

2023

To broaden access to HIV viral load monitoring (VLM), the use of blood samples from dried blood spots (DBS) or point-of-care (POC) devices, could be of great help in settings...

Gay community involvement and the sexual health behaviors of sexual minority men: A systematic review and directions for future research

2023

AbstractConsiderable research has examined how involvement in gay-affiliated communities is associated with sexual health behaviors in sexual minority men (i.e., gay, bisexual, and other men who have sex with men),...

Antivirals for prevention of hepatitis B virus mother-to-child transmission in human immunodeficiency virus positive pregnant women co-infected with hepatitis B virus

2023

BACKGROUND: Hepatitis B virus (HBV)-human Immunodeficiency virus (HIV) co-infection promotes an aggressive disease course of HBV infection. In the only available non-Cochrane systematic review on antiviral therapy during pregnancy for...

The association between HIV diagnosis disclosure and adherence to anti-retroviral therapy among adolescents living with HIV in Sub-Saharan Africa: A systematic review and meta-analysis

2023

INTRODUCTION: Nine in ten of the world’s 1.74 million adolescents living with human immunodeficiency virus (ALHIV) live in Sub-Saharan Africa. Suboptimal adherence to antiretroviral therapy (ART) and poor viral suppression...

Global associations of key populations with HIV-1 recombinants: A systematic review, global survey, and individual participant data meta-analysis

2023

INTRODUCTION: Global HIV infections due to HIV-1 recombinants are increasing and impede prevention and treatment efforts. Key populations suffer most new HIV infections, but their role in the spread of...

SARS-CoV-2 vaccine immunogenicity for people living with HIV: A systematic review and meta-analysis

2023

Background: Previous publications on the immunogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in people living with HIV (PLWH) have reported inconsistent results. Additionally, a meta-analysis investigating the immunogenicity...

A systematic review and meta-analysis of the global prevalence and determinants of COVID-19 vaccine acceptance and uptake in people living with HIV

2023

People living with HIV (PLHIV) are at higher risk of poor outcomes of SARS-CoV-2 infection. Here we report the pooled prevalence of COVID-19 vaccine acceptance/uptake and determinants among this vulnerable...

Geographic and population distributions of human immunodeficiency virus (HIV)-1 and HIV-2 circulating subtypes: A systematic literature review and meta-analysis (2010–2021)

2023

BACKGROUND: HIV poses significant challenges for vaccine development due to its high genetic mutation and recombination rates. Understanding the distribution of HIV subtypes (clades) across regions and populations is crucial....

A scoping review on COVID-19 vaccine hesitancy among the lesbian, gay, bisexual, transgender, queer, intersex and asexual (LGBTQIA+) community and factors fostering its refusal

2023

BACKGROUND: The ramifications of the existing crisis caused by the coronavirus pandemic are sensed in all walks of life. Among the various efforts made to curb the spread of this...

Review of antiretroviral therapy coverage in 10 highest burden HIV countries in Africa: 2015–2020

2023

Africa is responsible for two-thirds of the global total of new HIV infections. South Africa, Nigeria, Mozambique, Uganda, Tanzania, Zambia, Zimbabwe, Kenya, Malawi, and Ethiopia were responsible for 80% of...

What factors are associated with willingness to use HIV pre-exposure prophylaxis (PrEP) among U.S. men who have sex with nen not on PrEP? A systematic review and meta-analysis

2023

Pre-exposure prophylaxis (PrEP), an antiretroviral medication to prevent HIV, is becoming more widely available in the United States since the Federal Drug Administration approved it in 2012. However, PrEP use...

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