SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Revisiting the prevalence of unhealthy alcohol use among ethnic minority immigrant gay, bisexual men, and other men who have sex with men in North America: A systematic review and meta-analysis

2024

Unhealthy alcohol use is a significant public health concern among ethnic minority immigrant gay, bisexual men, and other men who have sex with men (GBMSM) in North America. The definition...

Proportion of active tuberculosis among HIV-infected children after antiretroviral therapy in Ethiopia: A systematic review and meta-analysis

2024

Despite effectiveness of antiretroviral therapy in reducing mortality of opportunistic infections among HIV infected children, however tuberculosis (TB) remains a significant cause for morbidity and attributed for one in every...

Genetic variation on dolutegravir pharmacokinetics and relation to safety and efficacy outcomes: A systematic review

2024

BACKGROUND: Dolutegravir (DTG) is an antiviral agent used for the treatment of HIV, however, there is uncertainty over the influence of genetic variation on DTG exposure, and whether it has...

Association of exposure to air pollutants and risk of mortality among people living with HIV: A systematic review

2024

Background People living with HIV (PLWH) are more vulnerable to infectious and non-infectious comorbidities due to chronic inflammation and immune dysfunction. Air pollution is a major global health risk, contributing...

Anti-cytomegalovirus preemptive therapy to prevent cytomegalovirus disease in HIV-infected patients: A systematic review

2023

BACKGROUND: HIV patients are at higher risk of contracting and developing into an asymptomatic form of CMV infection. This review aimed to evaluate the efficacy and safety of preemptive therapy...

Health economic analyses of latent tuberculosis infection screening and preventive treatment among people living with HIV in lower tuberculosis incidence settings: A systematic review

2023

Introduction: In lower tuberculosis (TB) incidence countries (<100 cases/100,000/year), screening and preventive treatment (PT) for latent TB infection (LTBI) among people living with HIV (PLWH) is often recommended, yet guidelines...

Immediate treatment for recent hepatitis C infection in people with high-risk behaviors: A systematic review and meta-analysis

2023

BACKGROUND AND AIMS: Direct-acting antivirals (DAAs) are almost exclusively approved for the treatment of chronic HCV. This poses a significant barrier to the treatment of recently acquired HCV because of...

A scoping review of lung function in children and adolescents living with HIV in the era of antiretroviral treatment

2023

Background: Human immunodeficiency virus (HIV) in children and adolescents remains an important health challenge in many countries and is commonly associated with lung disease. The introduction of antiretroviral therapy (ART) has...

The risk of sexual transmission of HIV in individuals with low-level HIV viraemia: A systematic review

2023

BACKGROUND: The risk of sexual transmission of HIV from individuals with low-level HIV viraemia receiving antiretroviral therapy (ART) has important public health implications, especially in resource-limited settings that use alternatives...

Barriers to pre-exposure prophylaxis (PrEP) use for HIV: An integrative review

2023

OBJECTIVES: to identify and synthesize scientific evidence on the barriers and difficulties for Pre-exposure Prophylaxis (PrEP) use and compliance for HIV. METHODS: an integrative literature review, using the MEDLINE/PubMed, Cumulative...

New treatment strategies for HIV-positive cancer patients undergoing anticancer medical treatment: Update of the literature

2023

The introduction of highly active antiretroviral therapy (ART) has deeply modified the outcome of HIV patients by improving their overall survival and ameliorating their quality of life (QoL). The prolongation...

A review of bidimensional acculturation and STI/HIV-related sexual risk behaviours among Hispanic youth

2023

A growing body of research suggests that acculturation may play a role in the disproportionate likelihood of sexual risk behaviour and STI/HIV infection among Hispanic youth in the USA. We...

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