SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Systematic review of neighborhood factors impacting HIV care continuum participation in the United States

2023

Social determinants have been increasingly implicated in accelerating HIV vulnerability, particularly for disenfranchised communities. Among these determinants, neighborhood factors play an important role in undermining HIV prevention. However, there has...

The influence between C-C chemokine receptor 5 (CCR5) genetic polymorphisms and the type-1 human immunodeficiency virus (HIV-1): A 20 years review

2023

Acquired Immune Deficiency Syndrome (AIDS) is an infectious disease caused by the types 1 and 2 Human Immunodeficiency Virus (HIV-1 and HIV-2). Clinical outcomes in patients are highly varied and...

Mapping the effectiveness of integrating mental health in HIV programs: A scoping review

2023

INTRODUCTION: Mental health and substance abuse issues are increasing among HIV-positive people, and it negatively impacts health outcomes like engagement, retention in HIV care, and adherence to ART. Thus, national...

Nutritional status and its determinants among adolescents with HIV on anti-retroviral treatment in low- and middle-income countries: A systematic review and meta-analysis

2023

Purpose This review aimed to determine what methods are used to assess nutritional status, the levels of nutritional status, determinants of undernutrition, and nutritional interventions employed for adolescents with HIV...

Examining the relationship between HIV-related stigma and the health and wellbeing of children and adolescents living with HIV: A systematic review

2023

Human immunodeficiency virus (HIV) affects millions of people globally. The associated stigma remains a challenge for individuals living with HIV and children and adolescents face the additional challenge of withstanding...

Effectiveness of behavioural economics informed interventions for the prevention, screening, and antiretroviral treatment of HIV infection: A systematic review of randomized controlled trials

2023

Failure to meet international targets set for the human immunodeficiency virus HIV pandemic suggests that more effective public health strategies are needed. New strategies informed by behavioural economics are now...

Coronavirus (COVID-19) and sexualised drug use among men who have sex with men: A systematic review

2023

Drug-related harms, including harms from sexualised drug use (SDU), are disproportionately experienced by sexual and gender minority people, relative to their majority counterparts. Chemsex, a type of SDU practiced mainly...

Alcohol use and associated risk factors among female sex workers in low- and middle-income countries: A systematic review and meta-analysis

2023

Due to its widespread use in the sex work industry, female sex workers (FSWs) in low- and middle-income countries (LMICs) are at high risk of harmful alcohol use and associated...

A systematic review and meta-analysis on the impact of statin treatment in HIV patients on antiretroviral therapy

2023

The rate of new human immunodeficiency virus (HIV) infections globally is alarming. Although antiretroviral therapy (ART) improves the quality of life among this group of patients, ARTs are associated with...

Pharmacokinetics of antiretroviral drugs in older people living with HIV: A systematic review

2023

Background and objective: The life expectancy of people living with HIV (PLWHIV) has significantly improved in recent decades, mostly due to antiretroviral (ARV) therapy. Aging can affect the pharmacokinetics of drugs...

The incidence rate of tuberculosis and its associated factors among HIV-positive persons in Sub-Saharan Africa: A systematic review and meta-analysis

2023

Background Tuberculosis, along with HIV, is the leading cause of mortality and morbidity globally. Despite the fact that several primary studies have been conducted on the incidence rate of tuberculosis...

HPV infection profiles among people living with HIV and HPV vaccine acceptance among individuals with different HIV infection statuses in China: A systematic review and meta-analysis

2023

To understand the HPV infection profiles among Chinese HIV/AIDS patients and the HPV vaccine acceptance among unvaccinated Chinese people with different HIV infection statuses after the HPV vaccine launch in...

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