SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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A review of serious gaming as an intervention for HIV prevention

2023

PURPOSEOF REVIEW: Young people face the highest number of new HIV infections globally. With today’s increasing access to smartphones, serious games have been viewed as an effective means of improving...

Barriers and facilitators to acceptability and uptake of pre-exposure prophylaxis (PrEP) among Black women in the United States: A systematic review

2023

OBJECTIVES: Pre-exposure prophylaxis (PrEP) provides a salient avenue to address the profound HIV-related health disparities that Black women in the United States face. This systematic review assessed the acceptability of...

Prevalence and risk factors of tuberculosis among people living with HIV/AIDS in China: A systematic review and meta-analysis

2023

OBJECTIVE: To estimate the prevalence and risk factors associated with tuberculosis (TB) among people living with human immunodeficiency virus (HIV) infection/acquired immunodeficiency syndrome (AIDS) in China. METHODS: A systematic review...

The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: A systematic review and meta-analysis

2023

BACKGROUND: Non-communicable diseases (NCDs) are increasing among people living with HIV (PLHIV), especially in Sub-Saharan Africa (SSA). We determined the prevalence of NCDs and NCD risk factors among PLHIV in...

Health facility-based interventions and the uptake of contraception among people living with HIV: A systematic review & meta-analysis

2023

BACKGROUND OBJECTIVES: The prong 2 of 4 prong strategy introduced by the World Health Organization aims at averting unintended pregnancies among people living with HIV (PLHIV). This systematic review aimed...

Inferring the multiplicity of founder variants initiating HIV-1 infection: A systematic review and individual patient data meta-analysis

2023

Background: HIV-1 infections initiated by multiple founder variants are characterised by a higher viral load and a worse clinical prognosis than those initiated with single founder variants, yet little is known...

An overview of programmatic indicators to monitor the roll-out of HIV preexposure prophylaxis

2023

Preexposure prophylaxis (PrEP) is increasingly implemented in national HIV prevention programmes through routine care. Monitoring will be vital to understand whether programmes succeed in engaging people into using PrEP appropriately,...

Safety considerations in the management of hepatitis C and HIV co-infection

2023

INTRODUCTION: Both HCV and HIV are highly prevalent infections with current estimates of 57 and 38 million people infected worldwide, respectively. Oral antivirals can be curative for HCV and rescue...

Comparison of clinical manifestations in mpox patients living with HIV versus without HIV: A systematic review and meta-analysis

2023

INTRODUCTION: Currently, many cases of mpox patients living with the human immunodeficiency virus (HIV) have been reported. Immunocompromised mpox patients including those living with HIV are noted for an increased...

Effectiveness of vaccination against SARS-CoV-2 and the need for alternative preventative approaches in immunocompromised individuals: A narrative review of systematic reviews

2023

INTRODUCTION: Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including administration of booster doses, continues to be the most effective method for controlling COVID-19-related complications including progression to severe...

Barriers to uptake of PrEP across the continuum among transgender women: A global scoping review

2023

BACKGROUND: Although preexposure prophylaxis (PrEP) has demonstrated high efficacy for HIV prevention, rates of PrEP uptake remain low among the transgender population, especially in transgender women (TGW). We conducted this...

The use of azithromycin and pyrimethamine for treatment of cerebral toxoplasmosis in human immunodeficiency virus-infected patients: A systematic review

2023

PURPOSE: Toxoplasma gondii is a parasite that is widely distributed around the globe and can cause brain inflammation, particularly in immunosuppressed patients such as those diagnosed with human immunodeficiency virus...

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