SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Bidirectional relationship between HIV/HBV infection and comorbid depression and/or anxiety: A systematic review on shared biological mechanisms

2023

Background: Mental disorders that are comorbid with chronic infectious diseases may worsen clinical outcomes and patients’ quality of life. We hypothesized that depression and/or anxiety syndromes or symptoms comorbid with...

Chemsex and chemsex associated substance use among men who have sex with men in Asia: A systematic review and meta-analysis

2023

BACKGROUND: The prevalence of chemsex has been reported by multiple systematic reviews among men who have sex with men (MSM) focussing predominantly on the Global North. An Asian perspective with...

Public health services and intersectional stigma: A social sciences perspective with implications for HIV service design and delivery

2023

PURPOSE OF REVIEW: Understanding stigma is important for improving HIV care services and gaps in HIV service delivery have been attributed to stigma. This review article synthesizes recent evidence on...

Prediction models for cardiovascular disease risk among people living with HIV: A systematic review and meta-analysis

2023

Background: HIV continues to be a major global health issue. The relative risk of cardiovascular disease (CVD) among people living with HIV (PLWH) was 2.16 compared to non-HIV-infections. The prediction of...

Monkeypox epidemiology, clinical presentation, and transmission: A systematic review

2023

BACKGROUND: The new zoonotic viral infection, monkeypox, is a global health issue. Our study aimed at studying the epidemiology, clinical presentation, complications, case fatality rate, and transmission among the present...

Adverse perinatal outcomes associated with antiretroviral therapy in women living with HIV: A systematic review and meta-analysis

2023

BACKGROUND: Maternal HIV infection is associated with an increased risk of adverse perinatal outcomes. The World Health Organization (WHO) recommends immediate initiation of lifelong antiretroviral therapy (ART) for all people...

Doxycycline prophylaxis for the prevention of bacterial sexually transmitted infections (STIs)

2023

Key take-home messages

A scoping review on the effects of COVID-19 on syringe service programs in the United States

2023

The COVID-19 pandemic has had worldwide impacts, including disrupting community services. One interrupted service was syringe service programs (SSPs), community-established initiatives that provide sterile supplies and aid in overcoming addiction...

Traditional male circumcision and the risk for HIV transmission among men: A systematic review

2023

OBJECTIVES: To synthesise evidence to determine whether, in contrast to medical male circumcision, traditional male circumcision (TMC) practices may contribute to HIV transmission and what the impacts of TMC are...

Human papillomavirus prevalence in pregnant women living with human immunodeficiency virus infection: A scoping review of the literature

2023

Objectives Studies already pointed out the increased risk of human papillomavirus (HPV) positivity and the implied risk of cervical dysplasia and even cervical carcinoma in pregnant women with human immunodeficiency virus...

Fecal microbiota transplantation in human immunodeficiency virus-infected patient population: A systematic review and meta-analysis

2023

BACKGROUND: Patients with human immunodeficiency virus (HIV) infection suffer from alterations in gut microbiota due to recurrent gastrointestinal infections and systemic inflammation. Fecal microbiota transplantation (FMT) appears to be a...

Potentially inappropriate prescribing in older people living with HIV: A scoping review

2023

BACKGROUND: Antiretroviral therapy has transformed HIV from a progressive and often fatal infection to a chronic disease. Currently, people living with HIV (PLHIV) have near-normal life expectancy; however, they face...

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