SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The prevalence and moderating factors of sleep disturbances in people living with HIV: A systematic review and meta-analysis

2024

This systematic review and meta-analysis aimed to investigate the prevalence of self-reported sleep disturbances in people living with HIV considering the effects of age, depression, anxiety, CD4 cell counts, time...

Using machine learning models to plan HIV services: Emerging opportunities in design, implementation and evaluation

2024

HIV/AIDS remains one of the world’s most significant public health and economic challenges, with approximately 36 million people currently living with the disease. Considerable progress has been made to reduce...

Innovation and implementation determinants of HIV testing and linkage-to-care in the U.S.: A systematic review

2024

OBJECTIVE: To identify innovation and implementation determinants of HIV testing, diagnosis, and linkage-to-care in the U.S. DATA SOURCES AND STUDY SETTING: Between November 2020 and January 2022, a broad search...

Bone tissue changes in individuals living with HIV/AIDS: The importance of a hierarchical approach in investigating bone fragility

2024

Skeletal alterations and their complications can significantly impact the quality of life and overall prognosis of patients living with HIV (PLWHIV). Considering skeletal alterations are often asymptomatic and unapparent during...

Structural racism conceptualization and operationalization for research for the U.S. HIV epidemic: Findings from a scoping review and implications for advancing research for structural interventions

2024

In the U.S., inequities by race/ethnicity in health outcomes, such as in the HIV epidemic, are long standing but have come to the forefront during the COVID-19 pandemic. There is...

Current trends and future directions in probiotics research for HIV/AIDS

2024

AIM: This study aims to comprehensively and systematically review the current status of research on probiotics and HIV/AIDS, while also exploring future research hotspots and trends in this domain. METHODS:...

Genetic variation on dolutegravir pharmacokinetics and relation to safety and efficacy outcomes: A systematic review

2024

BACKGROUND: Dolutegravir (DTG) is an antiviral agent used for the treatment of HIV, however, there is uncertainty over the influence of genetic variation on DTG exposure, and whether it has...

Association of exposure to air pollutants and risk of mortality among people living with HIV: A systematic review

2024

Background People living with HIV (PLWH) are more vulnerable to infectious and non-infectious comorbidities due to chronic inflammation and immune dysfunction. Air pollution is a major global health risk, contributing...

Determinants of stillbirths in sub-Saharan Africa: A systematic review

2024

Background Sub-Saharan African (SSA) countries have high stillbirth rates compared with high-income countries, yet research on risk factors for stillbirth in SSA remain scant. Objectives To identify the modifiable risk...

Counseling supporting HIV self-testing and linkage to care among men who have se with men: Systematic review and meta-analysis

2024

BACKGROUND: Counseling supporting HIV self-testing (HIVST) is helpful in facilitating linkage to care and promoting behavior changes among men who have sex with men (MSM). Different levels of counseling support...

Tri-substituted 1,3,5-triazine-based analogs as effective HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs): A systematic review

2024

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) have significantly impacted the HIV-1 wild-type due to their high specificity and superior potency. As well as different combinations of NNRTIs have been used on...

Estimates of the prevalence of male circumcision in sub-Saharan Africa from 2010–2023—A systematic review and meta-analysis

2024

Background Male circumcision (MC) is a key part of the package of interventions to prevent HIV, the biggest health challenge in sub-Saharan Africa. Objective To estimate the male circumcision prevalence...

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