SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Acceptability and use of HIV self-testing among young people in sub-Saharan Africa: A mixed methods systematic review

2024

Background Young people (YP) are disproportionately affected by the HIV pandemic in sub-Saharan Africa (SSA), but testing rates remain low despite global targets of testing 95% of people with HIV...

Global and regional genetic diversity of HIV-1 in 2010-21: Systematic review and analysis of prevalence

2024

Background The extensive global genetic diversity of HIV-1 poses a major challenge to HIV vaccine development. We aimed to determine recent estimates of and changes in the global and regional...

A narrative review of novel agents for managing heavily treatment-experienced people living with HIV

2024

Objective: The objective of this review is to compare ibalizumab, fostemsavir, and lenacapavir, present the clinical trials evaluating each agent, and provide guidance on their use in highly-treatment experienced (HTE)...

Comparative efficacy of antifungal drugs for the treatment of oral candidiasis in HIV-positive patients: A Bayesian network meta-analysis

2024

Oral candidiasis infection is particularly prevalent among individuals in HIV-positive patients. Antifungal drugs have shown promising therapeutic effects in treating oral candidiasis in HIV-positive patients. However, the selection of specific...

HBV, HCV and HIV among inmates in Latin America and the Caribbean: A systematic review and meta-analysis

2024

OBJECTIVES: Hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (HIV) affect 340 million people worldwide and have a high impact on vulnerable populations. The aim of...

Patient and public involvement in HIV research: A mapping review and development of an online evidence map

2024

INTRODUCTION: Increasing evidence indicates the benefits of patient and public involvement (PPI) in medical research, and PPI is increasingly expected by funders and publishers. We conducted a mapping review of...

Prevention of viral hepatitis and HIV infection among people who inject drugs: A systematic review and meta-analysis

2024

This study aimed to explore the current evidence on preventing blood-borne virus infections among people who inject drugs (PWID). We conducted a comprehensive search across three databases (PubMed, Embase, Cochrane...

The safety and immunogenicity of vaccines administered to pregnant women living with HIV: A systematic review and meta-analysis

2024

Background Human Immunodeficiency Virus (HIV)-exposed uninfected (HEU) infants have a higher burden of infectious diseases related morbidity and mortality compared with HIV-unexposed uninfected (HUU). Immunization of pregnant women living with...

Health-related quality of life measures provide information on the contributors, components, and consequences of frailty in HIV: A systematic mapping review

2024

Purpose: Frailty in HIV is extensively explored in epidemiological and clinical studies; it is infrequently assessed as an outcome in routine care. The focus on health-related quality of life (HRQL) measures...

A contextualization of transgender women and condom use using the HIV syndemic framework: Scoping review

2024

Objective: To contextualize condom use in the transgender women population utilizing the HIV syndemic framework. Methods: Studies reporting condom use frequency and syndemic factors associated with HIV risk in transgender...

Doxycycline post-exposure prophylaxis for bacterial sexually transmitted infections: The current landscape and future directions

2024

PURPOSE OF REVIEW: The incidence of bacterial sexually transmitted infections (STI) continues to rise particularly among men who have sex with men (MSM). Doxycycline post-exposure prophylaxis (doxy-PEP) has emerged as...

Prevalence of oropharyngeal candidiasis and distribution of Candida species among people living with human immunodeficiency virus in Africa: A systematic review and meta-analysis

2024

BACKGROUND: The incidence of oropharyngeal candidiasis among people living with human immunodeficiency virus in Africa is on the rise. Oropharyngeal candidiasis is mainly caused by C.albicans; however, a shift in...

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