SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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A systematic review of implementation research on determinants and strategies of effective HIV interventions for men who have sex with men in the United States

2023

Men who have sex with men (MSM) are disproportionately affected by HIV, accounting for two-thirds of Men who have sex with men (MSM) are disproportionately affected by HIV, accounting for...

Clinical relevance of drug interactions in people living with human immunodeficiency virus on antiretroviral therapy—Update 2022: Systematic review

2023

BACKGROUND: The clinical outcomes of antiretroviral drugs may be modified through drug interactions; thus, it is important to update the drug interactions in people living with HIV (PLHIV). AIM: To...

Non-pharmacological interventions for improving sleep in people living with HIV: A systematic narrative review

2023

BACKGROUND: Sleep disturbances are common in people living with Human Immunodeficiency Virus (HIV) and may lead to poor adherence to antiretroviral therapy and worsen HIV symptom severity. Due to the...

Prevalence of sexualized drug use and risk of HIV among sexually active MSM in East and South Asian countries: Systematic review and meta-analysis

2023

Introduction: Sexualized drug use (SDU), the use of psychoactive drugs in the context of sexual intercourse, has been identified as a risk factor for HIV among men who have sex with...

Safety considerations in the management of hepatitis C and HIV co-infection

2023

INTRODUCTION: Both HCV and HIV are highly prevalent infections with current estimates of 57 and 38 million people infected worldwide, respectively. Oral antivirals can be curative for HCV and rescue...

Comparison of clinical manifestations in mpox patients living with HIV versus without HIV: A systematic review and meta-analysis

2023

INTRODUCTION: Currently, many cases of mpox patients living with the human immunodeficiency virus (HIV) have been reported. Immunocompromised mpox patients including those living with HIV are noted for an increased...

Highlighting and addressing barriers to widespread adaptation of HIV self-testing in the United States

2023

INTRODUCTION: HIV self-testing (HIVST), whereby an individual performs and interprets their own rapid screening test at home, is another tool to increase the proportion of at-risk individuals who know their...

Can contingency management solve the problem of adherence to antiretroviral therapy in drug-dependent individuals?

2023

Drug misuse among people living with HIV (human immunodeficiency virus) is associated with higher mortality. It is a frequently observed reason for treatment abandonment, with people who misuse drugs showing...

Perspectives of health workers engaging in task shifting to deliver health care in low-and-middle-income countries: A qualitative evidence synthesis

2023

BACKGROUND: Low- and middle-income countries (LMICs) are experiencing growing demand for healthcare services yet face a persistent shortage in access to specialist health workers (SHWs). Task shifting is an approach...

Lifetime prevalence and adherence rate of cervical cancer screening among women living with HIV: A systematic review and meta-analysis

2023

INTRODUCTION: Women living with HIV (WLWH) are more likely to develop cervical cancer. Screening and available healthcare can effectively reduce its incidence and mortality rates. We aimed to summarize the...

HIV treatment, antiretroviral adherence and AIDS mortality in people who inject drugs: A scoping review

2023

BACKGROUND: People who inject drugs (PWID) are a key population for the prevention and care of HIV infection. METHODS: This scoping review covers recent (post-2010) systematic reviews on engagement of...

Morbidity and mortality in tuberculosis associated immune reconstitution inflammatory syndrome in children living with HIV: A narrative review

2023

Tuberculosis-associated immune reconstitution syndrome (TB-IRIS) is an increasingly recognized complication of children living with HIV who are receiving treatment for active tuberculosis (TB). The purpose of the study was to...

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