SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Prevalence of fungemia in people with HIV: A systematic review and meta-analysis

2026

Prior to the introduction of antiretroviral therapy (ART), people with HIV (PWH) had high risk of fungemia. No systematic review has assessed the prevalence of fungemia in PWH after the...

Closing Diagnostic Gaps in Pediatric HIV: Innovations in Point-of-Care and Digital Monitoring with an Asia-Pacific Implementation Lens-A Systematic Review

2026

Background/Objectives: Pediatric HIV case-finding and monitoring remain constrained by delayed early infant diagnosis (EID), loss to follow-up, and limited viral load (VL) testing-challenges particularly consequential in the operationally diverse Asia-Pacific...

Global Perspectives on Pre-Exposure Prophylaxis: A Systematic Review and Meta-Analysis of Health Care Providers’ Awareness, Willingness, and Barriers

2026

This systematic review and meta-analysis aimed to assess health care providers’ awareness, willingness, and key barriers in implementing HIV pre-exposure prophylaxis (PrEP). The review followed the Preferred Reporting Items for...

Barriers and Facilitators Influencing PrEP Uptake Among Men Who Have Sex with Men and Transgender Women in the United States: A Systematic Review

2026

In the United States, men who have sex with men (MSM) and transgender women (TGW) have high HIV pre-exposure prophylaxis (PrEP) awareness, yet uptake rates remain extremely low. This signifies...

Interventions for thriving in HIV serodiscordant relationships in Sub-Saharan Africa: a scoping review

2026

BACKGROUND: HIV serodiscordant relationships, where one partner is HIV-positive and the other is HIV-negative, present unique challenges despite biomedical advances including Uƒ_%=ƒ_%U (Undetectableƒ_%=ƒ_%Untransmittable). Effective interventions are crucial to support these...

The Prevalence and Influencing Factors of Frailty Among Middle-Aged and Older Adults With HIV/AIDS From a Global Perspective: A Systematic Review and Meta-Analysis

2026

AIM: Currently, frailty has become a central issue in health management among middle-aged and older people living with HIV/AIDS (PLWHA) worldwide. The objective is to develop targeted strategies to improve...

The global epidemiology of injecting drug use, HIV, viral hepatitis and tuberculosis among people who are incarcerated: a multistage systematic review

2026

BACKGROUND: This global systematic review assesses the prevalence of injecting drug use (IDU) and key infectious diseases (HIV, hepatitis C virus [HCV], tuberculosis and hepatitis B virus [HBV]) among people...

Non-surgical periodontal treatment outcomes in patients with HIV under antiretroviral therapy: A systematic review

2026

Background/Objectives: This systematic review aimed to evaluate the clinical and immunological outcomes of non-surgical periodontal therapy (NSPT) in HIV-positive patients with periodontitis. Methods: Systematic search on four databases (PubMed, Scopus,...

Virologic suppression among HIV-positive pregnant and lactating women receiving antiretroviral therapy in Africa: A systematic review and meta-analysis

2026

BACKGROUND: The elimination of mother-to-child transmission of human immunodeficiency virus (HIV) is a key global public health priority. In Africa, virologic failure among people living with HIV continues to pose...

Alternative Administration of Antiretroviral Therapy in People with HIV Unable to Swallow: A Scoping Review

2026

PURPOSE: To review published evidence on alternative administration methods for antiretroviral therapy in patients unable to swallow tablets. METHODS: We conducted a scoping review using PubMed, Web of Science, and...

Leveraging the Barriers and Facilitators of Pre-exposure Prophylaxis (PrEP) Care Among Latino Men Who Have Sex with Men in the U.S. to Inform Intervention: A Systematic Literature Review (2018-2023)

2026

HIV disproportionately affects Latino men who have sex with men (LMSM) in the United States (U.S.). Pre-exposure prophylaxis (PrEP) reduces HIV transmission, but prescription and use rates remain low among...

Viral load suppression rate of third-line antiretroviral therapy and its association with gender among HIV patients after second-line treatment failure in Africa: A systematic review and meta-analysis

2025

INTRODUCTION: Previous works of literatures on the viral load suppression rate of third line antiretroviral therapy in Africa has produced inconsistent and inconclusive results, with rates varying between 62% and...

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