SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Adverse perinatal outcomes associated with antiretroviral therapy in women living with HIV: A systematic review and meta-analysis

2023

BACKGROUND: Maternal HIV infection is associated with an increased risk of adverse perinatal outcomes. The World Health Organization (WHO) recommends immediate initiation of lifelong antiretroviral therapy (ART) for all people...

Doxycycline prophylaxis for the prevention of bacterial sexually transmitted infections (STIs)

2023

Key take-home messages

A scoping review on the effects of COVID-19 on syringe service programs in the United States

2023

The COVID-19 pandemic has had worldwide impacts, including disrupting community services. One interrupted service was syringe service programs (SSPs), community-established initiatives that provide sterile supplies and aid in overcoming addiction...

Traditional male circumcision and the risk for HIV transmission among men: A systematic review

2023

OBJECTIVES: To synthesise evidence to determine whether, in contrast to medical male circumcision, traditional male circumcision (TMC) practices may contribute to HIV transmission and what the impacts of TMC are...

Human papillomavirus prevalence in pregnant women living with human immunodeficiency virus infection: A scoping review of the literature

2023

Objectives Studies already pointed out the increased risk of human papillomavirus (HPV) positivity and the implied risk of cervical dysplasia and even cervical carcinoma in pregnant women with human immunodeficiency virus...

Fecal microbiota transplantation in human immunodeficiency virus-infected patient population: A systematic review and meta-analysis

2023

BACKGROUND: Patients with human immunodeficiency virus (HIV) infection suffer from alterations in gut microbiota due to recurrent gastrointestinal infections and systemic inflammation. Fecal microbiota transplantation (FMT) appears to be a...

Potentially inappropriate prescribing in older people living with HIV: A scoping review

2023

BACKGROUND: Antiretroviral therapy has transformed HIV from a progressive and often fatal infection to a chronic disease. Currently, people living with HIV (PLHIV) have near-normal life expectancy; however, they face...

Brief interventions for alcohol misuse among people living with HIV: A meta-analysis

2023

Background: One-third of people living with HIV (PLHIV) have alcohol misuse or alcohol use disorders which negatively affect course and outcome of HIV. Objectives: The meta-analysis sought to evaluate the effectiveness of...

Perspectives and thoughts of pregnant women and new mothers living with HIV receiving peer support: A mixed studies systematic review

2023

AIM: The aim of this study was to systematically consolidate evidence on perspectives and thoughts of women living with HIV regarding the peer support they have encountered during pregnancy and...

Factors associated with sexually transmitted shigella in men who have sex with men: A systematic review

2023

Background: Outbreaks of sexually transmitted shigella have been reported in men who have sex with men (MSM) since the 1970s and present a major public health issue. Understanding the factors associated...

Metabolic syndrome among people living with HIV in Ethiopia: A systematic review and meta-analysis

2023

BACKGROUND: Human Immuno-deficiency Virus (HIV) infection and antiretroviral therapy (ART) can cause metabolic disorders such as lipodystrophy, dyslipidemia, and insulin resistance, all of which are symptoms of metabolic syndrome (MetS)....

Prevalence and risk factors of cardiovascular disease among people living with HIV in the Asia-Pacific region: A systematic review

2023

BACKGROUND: Cardiovascular diseases (CVD) due to atherosclerosis have become one of the major causes of death among people living with HIV (PLHIV) since effective antiretroviral therapy (ART) has been available...

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