SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Comparing the effectiveness and adverse events of intranasal and intramuscular naloxone formulations for opioid overdose reversal

2023

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Promising practices for the design and implementation of sexuality education programmes for youth in India: A scoping review

2023

Sexual violence and HIV/AIDS are major public health concerns in India. By promoting bodily autonomy, wellbeing, and dignity through knowledge and skills, comprehensive sexuality education for young people can help...

Prevalence and factors associated with hypertension among peoples living with HIV in East Africa, a systematic review and meta-analysis

2023

Background In recent years, improved access to effective antiretroviral therapy has meant that people living with human immune virus are living longer than before. The burden of non-communicable diseases particularly,...

How much does HIV self-testing cost in low and middle income countries? A systematic review of evidence from economic studies

2023

OBJECTIVES: HIV self-testing (HIVST) has been proposed as an innovative strategy to diagnose human immunodeficiency virus (HIV). While HIVST offers the potential to broaden accessibility of early HIV diagnosis and...

Non-adherence to anti-retroviral therapy among adult people living with HIV in Ethiopia: Systematic review and meta-analysis

2023

Human immunodeficiency virus remains a global public health problem. Despite efforts to determine the prevalence of non-adherence to ART and its predictors in Ethiopia, various primary studies presented inconsistent findings....

A review of factors associated with methadone maintenance treatment adherence and retention in Vietnam

2023

BACKGROUND: Starting in 2008, Vietnam’s national MMT program expanded quickly, but it is struggling with increasing attrition rates and poor adherence among patients. Several studies have reported on MMT retention...

A scoping review of knowledge, awareness, perceptions, attitudes, and risky behaviors of sexually transmitted infections in Southeast Asia

2023

This scoping review synthesizes literature to examine the extent of research focusing on knowledge, awareness, perceptions, attitudes, and risky behaviors related to sexually transmitted infections (STIs) in Southeast Asia (SEA)....

Epidemiology of injecting drug use, prevalence of injecting-related harm, and exposure to behavioural and environmental risks among people who inject drugs: A systematic review

2023

Background People who inject drugs are exposed to various and changing risk environments and are at risk of multiple harms related to injecting drug use (IDU). We aimed to undertake...

New onset type 2 diabetes mellitus risks with integrase strand transfer inhibitors-based regimens: A systematic review and meta-analysis

2023

Objectives: The development of diabetes mellitus (DM) in patients taking integrase strand transfer inhibitors (INSTIs) has raised concerns. It’s critical because, in most guidelines, INSTIs are the preferred third agent at...

The interplay among HIV, monocytes/macrophages, and extracellular vesicles: A systematic review

2023

Despite effective antiretroviral therapies, chronic inflammation and spontaneous viral “blips” occur in HIV-infected patients. Given the roles for monocytes/macrophages in HIV pathogenesis and extracellular vesicles in intercellular communication, we performed...

Characterizing blood pressure trajectories in people living with HIV following antiretroviral therapy: A systematic review

2023

Objectives: The advent of antiretroviral therapy (ART) has reduced AIDS-related morbidity and mortality among people living with HIV (PLWH). Due to increased survival, PLWH have now been found to be at...

Prevalence and variability of HIV/AIDS-associated neurocognitive impairments in Africa: A systematic review and meta-analysis

2023

Background: HIV/AIDS-associated neurocognitive impairments negatively affect treatment adherence, viral load suppression, CD4 count, functionality, and the overall quality of life of people with seropositive status. However, huge variability is observed across...

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