Strategies for improving the lives of US women aged 40 and above living with HIV/AIDS: An evidence map


BACKGROUND: While in its early years the HIV epidemic affected primarily the male and the young, nowadays, the population living with HIV/AIDS is approximately 24% women, and its age composition has shifted towards older ages. Many of the older women who live with HIV/AIDS also live with the medical and social conditions that accompany aging. This work aims to identify and characterize empirical studies of strategies for the comprehensive management of women over 40, including transgender women, who live with HIV/AIDS. Forty was chosen as an operational age cutoff to identify premenopausal women who are less likely to bear children, as well as peri- and postmenopausal women. METHODS: We conducted a literature search after discussions with a diverse panel of content experts and other stakeholders and developed an evidence map that identified 890 citations that address questions having to do with programs and barriers to engaging with programs, as well as the role of insurance and comorbidities, and have enrolled older women who live with HIV/AIDS. RESULTS: Of these, only 37 (4%) reported results of interest for women over 40 who live with HIV/AIDS, or examined interactions between gender and older age that would allow predictions in this subgroup. Few of the 37 eligible studies focused on women facing obvious challenges, such as immigrants, transgender, physically abused, or those recently released from prison. No studies focused on women caring for dependents, including children and grandchildren, or those diagnosed after age 40. CONCLUSION: The evidence base that is directly applicable to women over 40 who live with HIV/AIDS in the USA is limited, and the research need is broad. We propose research prioritization strategies for this population


Adam GP, Di M, Cu-Uvin S, Halladay C, Smith BT, Iyer S, Trikalinos TA




  • Determinants of Health
    • Employment
    • Abuse
  • Population(s)
    • Women
    • Immigrants/Refugees/Non-status
    • Transgender communities
    • People who use drugs
    • Ethnoracial communities
    • Older adults (>50 years)
  • Engagement and Care Cascade
    • Linkage/engagement in care
  • Substance Use
    • Alcohol
    • Nonmedicinal drugs
    • Tobacco
  • Mental Health
    • Depression
    • Psychiatric disorders
  • Co-infections
    • Hepatitis B, C
  • Co-morbidities
    • Cardiovascular


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