Strategies for the prevention of mother to child transmission in Western countries: An update


BACKGROUND: During the last decades remarkable scientific advances have been made toward the prevention of HIV mother-to-child transmission, in particular in developed nations. The aim of this review was to analyze the latest findings and available international recommendations on the prevention of HIV mother-to-child transmission in high-income countries. METHODS: We performed a literature search of the Cochrane Library, MEDLINE by PubMed and EMBASE from database inception through June 2014, using the following terms: HIV, mother-to-child transmission and mother-to-child-transmission prevention. All types of articles in the English language were included. US and available European guidelines were searched and included in the analysis. RESULTS: One hundred fifty articles were selected for inclusion in this review. CONCLUSIONS: Global epidemiology of HIV infection is rapidly evolving, in particular in high-resource countries. The interpretation of clinical and epidemiological studies is crucial for the development of evidence-based recommendations to guide the management of HIV mother-to-child transmission. Although significant progress has been made, heterogeneity between countries in specific interventions still exists, which may address future research.


Sollai S, Noguera-Julian A, Galli L, Fortuny C, Deyà Á, de Martino M, Chiappini E.




  • Population(s)
    • Women
    • Children or Youth (less than 18 years old)
  • Prevention
    • Biomedical interventions


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