The HIV-related risk factors of the cisgender male sexual partners of transgender women (MSTW) in the United States: A systematic review of the literature


Cisgender male sexual partners of transgender women (MSTW) may be at risk for HIV infection. We performed a review of HIV risk factors among MSTW. We searched PubMed database for empirical quantitative U.S.-based studies that included MSTW and were published in English up to November 2018. Of the 4,680 total papers identified, 6 unique studies were included. MSTW displayed heterogeneity in HIV risk factors (e.g., condom use, sexual partners, sexual positions, substance use). In our exploratory meta-analyses, estimated prevalence of self-reported HIV positive status among MSTW was 30.6%, HIV unknown status was 8.8%, and self-reported condomless anal sex with transgender women was 46.1%. Reports of sexual health communication with transgender women was low. More research on MSTW populations is needed to better understand this population’s unique needs in the context of recent advancements in HIV prevention


Restar AJ, Surace A, Ogunbajo A, Edeza A, Kahler C




  • Epidemiology and Determinants of Health
    • Epidemiology
  • Population(s)
    • Transgender communities
  • Substance Use
    • Alcohol
    • Nonmedicinal drugs


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