SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

BACKGROUND: Human immunodeficiency virus (HIV) infection remains a significant global health challenge, with Kaposi’s sarcoma (KS) being one of the most common AIDS-defining cancers. This study aimed to investigate the...

Pregnancy introduces significant physiological changes that alter the pharmacokinetics (PK) of antiretroviral therapy (ART), impacting its safety and efficacy in HIV-positive women. Optimizing ART during pregnancy is critical to maintaining...

OBJECTIVES: The average age of a person living with HIV in high-income countries is increasing, as are rates of multimorbidity and frailty. To meet these needs, existing services must adapt....

INTRODUCTION: The World Health Organization (WHO) recommends the use of antiretroviral drugs as post-exposure prophylaxis (PEP) for preventing HIV acquisition for occupational and non-occupational exposures. To inform the development of...

BACKGROUND: HIV/AIDS has been a global health crisis for over 4 decades. Network models, which simulate human behavior and intervention impacts, have become an essential tool in guiding HIV prevention...

Background: In Africa, depressive symptoms are prevalent among people living with HIV (PLHIV), significantly impacting their adherence and overall quality of life. The combined burden of HIV and depressive symptoms worsens...

Background Self-sampling and self-testing have been increasingly used for sexually transmitted infections (STIs) and quickly became widespread during the COVID-19 pandemic. User acceptability, preferences, and experiences are important factors affecting...

BACKGROUND: Long-acting injectable antiretroviral therapy (LAI ART) is a new, and innovative approach to HIV treatment, designed to address several challenges, including the adherence issues associated with daily oral ART....

Suicide is a leading cause of death in Canada, with men being three times more likely to die from suicide compared with the rest of the population. Among Canadian men,...

OBJECTIVE: To evaluate the evidenceAÿregarding the association between antiretroviral therapy and dental caries in children and adolescents with HIV. METHODS: Searches were conducted in five international databases (PubMed, Scopus, EMBASE,...

Human immunodeficiency virus (HIV) vaccine trials are needed in efforts to prevent infection and acquired immunodeficiency syndrome (AIDS). Like other types of research, HIV vaccine trials present benefits and risks...

Objectives Doxycycline post-exposure prophylaxis (doxyPEP) can reduce incident sexually transmitted infections including gonorrhoea for MSM and transgender women. Its effectiveness depends on the level of tetracycline resistance in Neisseria gonorrhoeae, which...