SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The prognosis characteristics of HIV/HBV co-infection after antiviral therapy: a comprehensive review

2026

Co-infection of HIV and HBV is still a major global public health concern. Co-infected people have a nearly threefold increased risk of end-stage liver disease, with a noticeably faster development...

Effectiveness of differentiated antiretroviral therapy delivery models for stable persons living with HIV in Africa: A systematic review and meta-analysis

2026

INTRODUCTION: Fundamental progress has been made in HIV care, and one of the major advances was the implementation of Differentiated Service Delivery (DSD) models. DSD models are important in reducing...

HIV prevention interventions for men who have sex with men

2026

Key take-home messages HIV prevention interventions for men who have sex with men can be classified into the following categories: individual, couple-based, or group behavioural interventions; and provider-based or structural-level...

Effectiveness of Telehealth in HIV Management for People Living with HIV and Key Populations: A Systematic Review of Models, Adherence, Viral Suppression, and Behavioral Outcomes

2026

Human Immunodeficiency Virus (HIV) is a global health problem that causes many deaths, especially in low- and middle-income countries (LMICs). Most HIV cases occur in sub-Saharan Africa and Asia. In...

Cancer in older adults living with HIV

2026

Key take-home messages Evidence shows that cancer risk among older people living with HIV is increased for some cancers (e.g., anal, lung, liver). Earlier initiation of antiretroviral therapy (ART) following...

Geospatial Approaches to HIV Care: a Scoping Review of Asset Mapping

2026

PURPOSE OF REVIEW: Asset mapping aims to engage members of a community to explore and map assets that are solutions to social issues such as homelessness or access to health...

Body composition, hepatic fat, metabolic, and safety outcomes of Tesamorelin, a GHRH analogue, in HIV-associated lipodystrophy: A meta-analysis of randomized controlled trials

2026

BACKGROUND: HIV-associated lipodystrophy leads to visceral fat accumulation, metabolic complications, body image concerns, medication non-adherence, and increased cardiovascular risks. We thought to assess the effects of Tesamorelin, a synthetic growth...

Models of primary health care for people living with HIV

2026

Key take-home messages

Comparing clinical outcomes of antibiotics for treating Mycobacterium avium complex infection in adults with HIV: A systematic review and network meta-analysis

2026

BACKGROUND: This study aims to identify the comparative effects of different drug regimens in treating Mycobacterium avium complex (MAC). METHODS: PubMed, EMBASE, CENTRAL, and EBSCO Open Dissertations were searched in...

HIV testing during systematic screening for tuberculosis among household contacts in high-tuberculosis burden settings: A systematic review and meta-analysis

2026

BACKGROUND: Tuberculosis household contacts are at elevated risk of HIV, and systematic screening for tuberculosis is an opportunity for people to know their status. We aimed to assess the coverage...

Preferences for long-acting antiretroviral therapy among people with HIV: A systematic review of discrete choice experiments

2026

BACKGROUND: Long-acting antiretroviral therapy (LA-ART) is emerging as a promising strategy to enhance treatment satisfaction and improve the quality of life for people living with HIV (PLWH). A comprehensive understanding...

Physical activity counseling for people living with HIV: A scoping review

2026

OBJECTIVE: To explore evidence on physical activity counseling for people living with HIV (PLHIV). METHODS: Searches covered earliest records in PubMed (1946), Embase (1947), Web of Science (1900), Scopus (1788),...

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