SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Comparative safety of B/F/TAF versus other antiretroviral therapy regimens for treatment-experienced people with HIV-1: A systematic literature review and network meta-analysis

2026

Aim: With modern antiretroviral therapy (ART), HIV-1 has now become a manageable chronic condition. Among treatment-experienced (TE) people with HIV-1 (PWH), ART regimens can influence metabolic and renal outcomes and...

Cause of death and risk of death for people living with HIV admitted to hospital: A systematic review and meta-analysis

2026

Introduction Despite increasing access to HIV treatment and care, HIV-associated deaths remain high. We aimed to summarize global and regional trends in risk and causes of death among people living...

Models of care for women living with HIV in Europe: A scoping review

2026

INTRODUCTION: With the widespread availability of antiretroviral therapy, human immunodeficiency virus (HIV) has become a chronic condition requiring long-term, integrated care. Women with HIV experience distinct clinical, reproductive, and psychosocial...

Guidance on the clinical management of HIV-1 persistent low-level viraemia on antiretroviral treatment: A scoping review and an international Delphi consensus

2026

Despite the success of antiretroviral therapy, a subset of people with HIV experience low-level viraemia (LLV), a challenging condition with inconsistent definitions and management across settings. We conducted a scoping...

Efficacy and safety of doravirine/islatravir for HIV-1: A GRADE-assessed systematic review and meta-analysis of randomized controlled trials

2026

Background: The combination of doravirine and islatravir (DOR/ISL) is a novel two-drug regimen for HIV-1. Early development faced challenges due to dose-dependent immunological signals. We aimed to synthesize the evidence on...

Systematic review of sexual violence against sex workers: Implications for mental and sexual health

2026

Background: Sex workers worldwide experience different forms of violence and stigma that increase the risk of adverse health outcomes. It is assumed that a discriminatory, criminalizing context as well as intersectional...

Empowering women living with HIV through partner-based interventions: A scoping review

2026

Spouses and partners play a crucial role in the well-being of women living with HIV (WLWH), especially in family-oriented cultures. This scoping review examined partner-inclusive interventions to strengthen support systems...

Prevalence of loneliness and social isolation among people living with HIV: A systematic review and meta-analysis

2026

Design A systematic review and meta-analysis. Data Sources PubMed, Cochrane Library, SciELO Citation Index (via Web of Science), Scopus, Embase, PsycArticles, and Cumulative Index to Nursing and Allied Health Literature...

Relationship quality among people living with HIV/AIDS: A systematic review and meta-analysis

2026

Background The aim of this systematic review and meta-analysis was to summarize the existing literature on the factors associated with relationship quality among people living with HIV (PLWH). Method A...

The association between food insecurity and adverse health outcomes in adults: An umbrella review of systematic reviews and meta-analyses

2026

Context An association of food insecurity (FI) with adverse health outcomes (AHOs) has been reported; however, the evidence in this context is still inconclusive. Objective The certainty and validity of...

Perinatal HIV in Europe: Clinical advances and psychosocial challenges—A scoping review

2026

Despite significant biomedical advances in the prevention of mother-to-child transmission (MTCT) of HIV, residual transmission and suboptimal maternal outcomes persist across Europe. The challenge is no longer primarily virological but...

Culturally competent HIV prevention for African, Caribbean, and Black communities and Indigenous Peoples

2026

Key take-home messages Developing culturally sensitive approaches and materials helps ensure HIV prevention interventions are relevant, acceptable, and responsive to the needs of the intended population groups. Close collaboration with...

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