SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Ingestible electronic sensors for monitoring real-time adherence to HIV pre-exposure prophylaxis and antiretroviral therapy

2022

PURPOSE OF REVIEW: This review summarizes the recent advancements and future directions of digital pill systems (DPS) – which utilize ingestible sensors to directly measure medication ingestion events in real-time...

HIV voluntary counseling and testing (VCT-HIV) effectiveness for sexual risk-reduction among key populations: A systematic review and meta-analysis

2022

Background: HIV disproportionately affects people who inject drugs, transgender people, sex workers, men who have sex with men, and incarcerated people. Recognized as key populations (KP), these groups face increased impact...

Pediatrics HIV-positive status disclosure and its predictors in Ethiopia: A systematic review and meta-analysis

2022

INTRODUCTION: HIV-positive status disclosure for children is challenging for family members, guardians, and healthcare professionals. Disclosure is very challenging, particularly for children, yet no systematic synthesis of evidence accurately measures...

Condom use and risk factors of inconsistent or low use of the condoms during heterosexual anal intercourse in sub-Saharan Africa: A scoping review

2022

BACKGROUND: Anal intercourse (AI) has been reported to be the riskiest among other sexual intercourses in spreading human immunodeficiency virus (HIV) and the risk could be minimized by the use...

The performance of using dried blood spot specimens for HIV-1 viral load testing: A systematic review and meta-analysis

2022

BACKGROUND: Accurate routine HIV viral load testing is essential for assessing the efficacy of antiretroviral treatment (ART) regimens and the emergence of drug resistance. While the use of plasma specimens...

The demographic and socioeconomic correlates of behavior and HIV infection status across sub-Saharan Africa

2022

Background: Predisposition to become HIV positive (HIV + ) is influenced by a wide range of correlated economic, environmental, demographic, social, and behavioral factors. While evidence among a candidate handful have...

Determinants of voluntary counseling and testing service uptake among adult sub-Saharan Africans: A systematic review and meta-analysis

2022

Objective: To examine the major determinants of VCT service uptake among adults in SSA. Methods: Electronic databases were searched to identify eligible English language publications. Reporting of the study selection...

Incidence and mortality of non-AIDS-defining cancers among people living with HIV: A systematic review and meta-analysis

2022

Background: Non-AIDS-defining cancers (NADCs) are now becoming a rising cause of morbidity among people living with HIV (PLHIV) in the highly active antiretroviral therapy (HAART) era. We conducted a systematic review...

Association of HIV infection with cardiovascular pathology based on advanced cardiovascular imaging: A systematic review

2022

Importance: HIV-associated cardiovascular disease is increasing in prevalence, but its mechanisms remain poorly understood. Objective: To systematically review data from advanced cardiovascular imaging studies evaluating computed tomographic coronary angiography, positron emission tomography...

What is the global prevalence of depression among men who have sex with men? A systematic review and meta-analysis

2022

Background: Depression due to stigma resulting from their sexual identity, isolation, social exclusion, and insufficient access to care and counseling services has become a health problem among men who have sex...

Does sickle cell disease protect against HIV infection: A systematic review

2022

OBJECTIVE: The aim of this systematic review was to investigate if SCD protects against HIV infection by determining the association between SCD and the incidence and virulence of HIV infection....

Linkage to HIV care following HIV self-testing among men: Systematic review of quantitative and qualitative studies from six countries in sub-Saharan Africa

2022

Gender disparities are pervasive throughout the HIV care continuum in sub-Saharan Africa, with men testing, receiving treatment, and achieving viral suppression at lower rates, and experiencing mortality at higher rates,...

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