SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Importance of male partner’s involvement in prevention of mother to child transmission of HIV/AIDS in Ethiopia: A systematic review and meta analysis until June 2021

2022

Background: To promote the prevention of mother-to-child transmission (PMTCT) of HIV/AIDS male partners play a significant role, especially in developing country were men’s are a decision maker in domestic activity. When...

Cabotegravir extended-release injectable suspension: A review in HIV-1 pre-exposure prophylaxis

2022

Cabotegravir extended-release (ER) injectable suspension (Apretude™) is the first long-acting injectable option to be approved for HIV-1 pre-exposure prophylaxis (PrEP). As an HIV-1 integrase strand transfer inhibitor, cabotegravir ER injectable...

Same-day and rapid initiation of antiretroviral therapy in people living with HIV in Asia. How far have we come?

2022

Human immunodeficiency virus (HIV) continues to be a major public health issue, and the effectiveness of HIV prevention, diagnosis, treatment, and care varies, particularly in the Asia-Pacific region. The rapid...

SARS-CoV-2: Review of conditions associated with severe disease and mortality

2022

The 2019 Coronavirus Virus Disease (COVID-19) represents a global public health challenge in the twenty-first century. As of June 2020, the virus had spread across 216 countries across the globe....

A Systematic review exploring the effect of human immunodeficiency virus on cardiac diseases

2022

Human immunodeficiency virus (HIV) primarily affects the immune systems, which, if progressed, will lead to acquired immunodeficiency syndrome (AIDS). Currently, there is no effective cure for the disease, and patients...

Oral health status of children and adolescents living with HIV undergoing antiretroviral therapy: A systematic review and meta-analysis

2022

Antiretroviral therapy (ART) increases the survival of HIV-infected children, but might also bring in oral health-related side effects and increase their risks of oral diseases. The review compared the oral...

Current perspectives on the determinants of acceptability of pre-exposure prophylaxis and nonoccupational post-exposure Prophylaxis among people at risk for HIV: A scoping review

2022

Pre-exposure prophylaxis (PrEP) and nonoccupational post-exposure prophylaxis (nPEP) were found to be effective HIV biomedical interventions. However, several barriers to acceptance of these interventions were discovered among populations at risk...

Impact of antiretroviral therapy on oral health among children living with HIV: A systematic review and meta-analysis

2022

Oral health is an integral component of general health and well-being but might be undermined among children living with HIV (CLWH) due to the condition itself or the antiretroviral therapy...

Neuroinflammation in HIV-associated depression: Evidence and future perspectives

2022

People living with HIV face a high risk of mental illness, especially depression. We do not yet know the precise neurobiological mechanisms underlying HIV-associated depression. Depression severity in the general...

Worldwide prevalence of human papillomavirus among pregnant women: A systematic review and meta-analysis

2022

Human papillomavirus (HPV) is the causative agent of cervical cancer and a suspected agent for ovarian and endometrial cancers in women. It is associated with adverse outcomes during pregnancy. To...

A review of supervised inhalation services in Canada

2022

Key take-home messages Reports from different Canadian provinces (British Columbia, Ontario, and Alberta) indicate that more individuals overdose by inhaling opioids (including fentanyl) compared to those who overdose via injection...

Risk heterogeneity in compartmental HIV transmission models of ART as prevention in Sub-Saharan Africa: A scoping review

2022

BACKGROUND: Transmission models provide complementary evidence to clinical trials about the potential population-level incidence reduction attributable to ART (ART prevention impact). Different modelling assumptions about risk heterogeneity may influence projected...

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