SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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A systematic review and meta-analysis on depression and associated factors among adult HIV/AIDS-positive patients attending ART clinics of Ethiopia: 2021

2021

INTRODUCTION: Depression is the most common mental health problem in people living with the human immune virus. It ranges from 11% to 63% in low- and middle-income countries. Depression was...

Point of care testing for infectious disease in Europe: A scoping review and survey study

2021

Background: Point of care testing (POCT) for infectious diseases is testing conducted near the patient. It allows clinicians to offer the most appropriate treatment more quickly. As POCT devices have...

Intersectoral costs of sexually transmitted infections (STIs) and HIV: A systematic review of cost-of-illness (COI) studies

2021

BACKGROUND: Sexually transmitted infections (STIs) and HIV can generate costs both within and outside the health sector (i.e. intersectoral costs). This systematic review aims (i) to explore the intersectoral costs...

Current approaches to HIV vaccine development: A narrative review

2021

INTRODUCTION: The development of an effective vaccine to protect against HIV is a longstanding global health need complicated by challenges inherent to HIV biology and to the execution of vaccine...

Meta-analysis on nicotine’s modulation of HIV-associated dementia

2021

HIV-Associated Dementia (HAD) is a significant comorbidity that many HIV-patients face. Our study utilized QIAGEN Ingenuity Pathway Analysis (IPA) to identify and analyze molecular profiles and pathways underlying nicotine’s impact...

HIV seroprevalence in five key populations in Europe: A systematic literature review, 2009 to 2019

2021

Background: In Europe, HIV disproportionately affects men who have sex with men (MSM), people who inject drugs (PWID), prisoners, sex workers, and transgender people. Epidemiological data are primarily available from...

Safety of tenofovir disoproxil fumarate for pregnant women facing the coronavirus disease 2019 pandemic

2021

We assessed the teratogenicity of tenofovir, a human immunodeficiency virus (HIV) drug similar to remdesivir that is currently being evaluated for the treatment of coronavirus disease 2019 (COVID-19). Using US...

A scoping review investigating relationships between depression, anxiety, and the PrEP care continuum in the United States

2021

Men who have sex with men and transgender women in the United States are at increased risk for HIV and may benefit from pre-exposure prophylaxis (PrEP), a once-a-day pill to...

Pre-exposure prophylaxis uptake, adherence, and persistence: A narrative review of interventions in the U.S

2021

Since 2012, HIV pre-exposure prophylaxis (PrEP) has been available to prevent HIV transmission; yet, uptake, adherence, and persistence to PrEP have been suboptimal. This narrative review examines the latest interventions...

Assessing inclusion of trans people in HIV national strategic plans: A review of 60 high HIV prevalence countries

2021

INTRODUCTION: Trans people are disproportionately impacted by HIV yet have not been adequately prioritized in national HIV responses or policy documents. This review aims to understand the extent of meaningful...

The likelihood of severe COVID-19 outcomes among PLHIV with various comorbidities: A comparative frequentist and Bayesian meta-analysis approach

2021

INTRODUCTION: The SARS-CoV-2 virus can currently pose a serious health threat and can lead to severe COVID-19 outcomes, especially for populations suffering from comorbidities. Currently, the data available on the...

Validated HIV knowledge scales for use with adults and adolescents: A systematic review

2021

HIV knowledge—the information a person possesses about HIV—is essential for the prevention and management of HIV. Therefore, the accurate measurement of HIV knowledge is important for both science and practice....

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