SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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What is known from the existing literature about how sleep is measured in HIV care? A scoping review

2024

The HIV care landscape has significantly altered over the past 30 years with advances in HIV medical treatment. Despite these medical advances, people living with HIV experience a significant number...

How does intersectionality impact the quality of healthcare services for Black women living with HIV?

2024

Women with HIV are affected more than men by intersecting discriminations. For Black women, additional discrimination can have a detrimental effect on their HIV care. An extended literature review of...

Evidence of zero-risk transmission of HIV in the era of antiretroviral therapy: A systematic review and meta-analyses

2024

OBJECTIVE: This systematic review aimed to assess the evidence on sexual transmission of HIV in high-income settings between serodiscordant couples where the index partner infected with HIV is on antiretroviral...

Real-world effectiveness and tolerability of Dolutegravir and Lamivudine 2-drug regimen in people living with HIV: Systematic literature review and meta-analysis

2025

Introduction: Dolutegravir (DTG) + lamivudine (3TC) demonstrated high rates of virologic suppression (VS) and low rates of virologic failure (VF), discontinuation, and drug resistance in randomized trials. Real-world evidence can support...

Impact of COVID-19 on utilization of healthcare services among people living with HIV (PLHIV): A systematic review

2025

Background and Objectives: People living with HIV/AIDS have been impacted notably by the COVID-19 pandemic in diverse dimensions. Although some impacts of COVID-19 on PLHIV have been well documented, there...

Systematic review on the compliance of WHO guidelines in the management of patients with advanced HIV disease in Africa: The case of cryptococcal antigen screening

2025

BACKGROUND: The World Health Organization (WHO) recommended cryptococcal antigen (CrAg) screening for people presenting with advanced HIV disease (AHD) and for those with positive CrAg without evidence of meningitis to...

Comparative efficacy of antifungal drugs for the treatment of oral candidiasis in HIV-positive patients: A Bayesian network meta-analysis

2024

Oral candidiasis infection is particularly prevalent among individuals in HIV-positive patients. Antifungal drugs have shown promising therapeutic effects in treating oral candidiasis in HIV-positive patients. However, the selection of specific...

A blueprint for large language model-augmented telehealth for HIV mitigation in Indonesia: A scoping review of a novel therapeutic modality

2025

Background: The HIV epidemic in Indonesia is one of the fastest growing in Southeast Asia and is characterised by a number of geographic and sociocultural challenges. Can large language models...

Food consumption and cardiovascular risk in children and adolescents living with HIV: A systematic review

2025

The aim of this systematic review was to summarize the dietary intake of children and adolescents living with HIV and its association with cardiovascular risk factors. PubMed/MEDLINE, Scopus, Web of...

Prevalence of suicidal ideation and associated factors among perinatal women living with HIV: A systematic review and meta-analysis

2025

Perinatal women living with HIV face increased susceptibility to mental health challenges, including suicidal ideation (SI). This study aimed to determine the prevalence of SI among perinatal women with HIV...

Low dietary diversity and associated factors among adult people with HIV patients attending ART clinics of Ethiopia. Systematic review and meta-analysis

2025

Introduction: Dietary diversity is the utilization of food and food groups consumed by individuals over 24 h, which is an indicator of a diet’s micronutrient adequacy. Dietary management in people with...

Additive effects of glutathione in improving antibiotic efficacy in HIV-M.tb co-Infection in the central nervous system: A systematic review

2025

BACKGROUND: HIV and tuberculosis (TB) co-infection poses a significant health challenge, particularly when involving the central nervous system (CNS), where it leads to severe morbidity and mortality. Current treatments face...

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