SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Weight gain, obesity, and the impact of lifestyle factors among people living with HIV: A systematic review

2024

HIV remains a significant health concern, but the advent of antiretroviral therapy (ART) has transformed it into a manageable chronic condition. However, weight gain and obesity pose a substantial challenge...

Challenges in elucidating HIV-1 genetic diversity in the Middle East and North Africa: A review based on a systematic search

2025

The extensive genetic diversity of HIV-1 represents a major challenge to public health interventions, treatment, and successful vaccine design. This challenge is particularly pronounced in the Middle East and North...

Self-reported sleep disturbances among people living with HIV in China: A systematic review and meta-analysis

2025

Objective: People living with HIV (PLWH) commonly face a range of health issues, among which sleep disturbances are common and are related to adverse health outcomes. This review aims to assess...

Impact of HIV-related stigma on antiretroviral therapy adherence, engagement and retention in HIV care, and transition to adult HIV care in pediatric and young adult populations living with HIV: A literature review

2024

Abstract HIV-related stigma is associated with negative effects on mental health and lower health-related quality of life in pediatric and young adult populations living with HIV. We reviewed literature on...

Kidney dysfunction and associated factors among adults living with human immuno-deficiency virus in Africa: A systematic review and meta-analysis

2025

Background Kidney dysfunction among adults living with Human Immuno-Deficiency Virus (HIV) increases the risk of drug-related side effects, acute kidney injury, hospitalization, and progression to end-stage kidney disease. In developing...

Invasive Neisseria meningitidis subtype C in gay, bisexual and other men who have sex with men: A systematic review

2024

INTRODUCTION: Outbreaks of invasive Neisseria meningitidis subtype C in networks of gay, bisexual and other men who have sex with men (MSM) have been reported. We aimed to explore any...

Barriers to HIV pre-exposure prophylaxis uptake for men who have sex with both men and women: A global scoping review

2025

BackgroundAlthough PrEP is a highly effective HIV prevention method, some groups are underrepresented in PrEP uptake. Much HIV prevention research groups gay, bisexual and other men who have sex with...

Economic evaluations of sexual and reproductive health (SRH) services in low- and middle-income countries (LMICs): A systematic review

2025

BACKGROUND: Sexual and reproductive health (SRH) programmes and services aim to prevent complications of pregnancy and childbirth, unintended pregnancies, unsafe abortions, complications caused by sexually transmitted infections, including HIV, sexual...

Prevalence and burden of HBV-HIV co-morbidity: A global systematic review and meta-analysis

2025

Introduction Hepatitis B is a serious liver infection caused by the hepatitis B virus (HBV). Because of the shared modes of transmission, co-infections of HBV are common among people living...

Does climate change threaten delivery of HIV care in resource-limited settings?

2025

PURPOSE OF REVIEW: Extreme weather events (EWEs) pose a challenge to achieving UNAIDS goal of eliminating HIV as a public health threat by 2030. This review summarizes recent findings describing...

Satisfaction with HIV/AIDS treatment and care services and its associated factors among adult people receiving antiretroviral therapy in Ethiopia: A systematic review and meta-analysis

2025

Objective To make healthcare programmes more patient-centred and efficient in light of limited resources, it is crucial to ensure patient satisfaction. There is limited information on the overall level of...

Impact of HIV infection on hepatocellular carcinoma: A long-term prognostic analysis

2025

Purpose: This study aims to explore the influence of human immunodeficiency virus (HIV) infection on the prognosis of patients with hepatocellular carcinoma (HCC). Methods: According to the search strategy, we...

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