SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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A meta-analysis of gray matter volume abnormalities in HIV patients

2023

HIV infection is known to have significant effects on central nervous system. This study conducted a meta-analysis of whole voxel-based morphometry (VBM) in HIV patients (N=435) and HIV-uninfected controls (N=397)....

Evaluation of HIV screening in hospital emergency services. Systematic review

2023

AIM: To evaluate HIV screening of people attending emergency services. DESIGN: Systematic review. DATA SOURCES: CINAHL Complete, Cochrane Library, Cuiden Plus, PubMed, PsycINFO, SCOPUS and Web of Science. REVIEW METHODS:...

Potentially inappropriate prescribing in older people living with HIV: A scoping review

2023

BACKGROUND: Antiretroviral therapy has transformed HIV from a progressive and often fatal infection to a chronic disease. Currently, people living with HIV (PLHIV) have near-normal life expectancy; however, they face...

The incidence rate of tuberculosis and its associated factors among HIV-positive persons in Sub-Saharan Africa: A systematic review and meta-analysis

2023

Background Tuberculosis, along with HIV, is the leading cause of mortality and morbidity globally. Despite the fact that several primary studies have been conducted on the incidence rate of tuberculosis...

SARS-CoV-2 vaccine immunogenicity for people living with HIV: A systematic review and meta-analysis

2023

Background: Previous publications on the immunogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in people living with HIV (PLWH) have reported inconsistent results. Additionally, a meta-analysis investigating the immunogenicity...

Safety of longer-term doxycycline use: A systematic review and meta-analysis with implications for bacterial sexually transmitted infection chemoprophylaxis

2023

BACKGROUND: Sexually transmitted infections (STIs) such as syphilis, gonorrhea, and chlamydia have significantly increased over the past decade in the United States. Doxycycline as chemoprophylaxis (i.e., postexposure prophylaxis) offers promise...

Can newborn infants with positive HIV soon after birth be diagnosed with intrauterine infection?

2023

BACKGROUND: Mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) can occur intrauterine, intrapartum, and postpartum. Currently, infants with confirmed positive results in virological tests before 48h of age are defined...

The global prevalence of suicidal ideation and suicide attempts among men who have sex with men: A systematic review and meta-analysis

2023

BACKGROUND: This study aimed to determine the global prevalence of suicidal ideation and attempts among men who have sex with men (MSM) as a systematic review, and meta-analysis. METHODS: For...

Extracorporeal life support for patients with newly diagnosed HIV and acute respiratory distress syndrome: A systematic review and analysis of individual patient data

2023

Extracorporeal membrane oxygenation (ECMO) may improve survival in patients with severe acute respiratory distress syndrome (ARDS). However, presence of immunosuppression is a relative contraindication for ECMO, which is withheld in...

HIV pre-exposure prophylaxis, blood donor deferral, occult infection, and risk of HIV transmission by transfusion: A fine balance between evidence-based donor selection criteria and transfusion safety

2023

Pre- and postexposure prophylaxis for human immunodeficiency virus (HIV) are key to reducing the transmission of this virus. Furthermore, low-toxicity, long-acting formulations provide additional clinical benefits, in particular easier adherence...

A systematic review of interventions for young men who have sex with men and young transgender women living with HIV

2023

Young men who have sex with men (YMSM) and young transgender women (YTGW) have unique challenges to HIV care. We conducted a systematic review to summarize behavioral and structural interventions...

Collection of menopause data in studies of women living with HIV: A systematic literature review

2023

Objectives An increasing number of women living with HIV are transitioning through midlife and menopause. Women living with HIV may experience earlier menopause and a higher symptom burden than women...

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