SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The clinical effectiveness of individual behaviour change interventions to reduce risky sexual behaviour after a negative human immunodeficiency virus test in men who have sex with men: Systematic and realist reviews and intervention development

2017

BACKGROUND: Men who have sex with men (MSM) experience significant inequalities in health and well-being. They are the group in the UK at the highest risk of acquiring a human...

New treatment strategies for HIV-positive cancer patients undergoing antiblastic chemotherapy

2016

INTRODUCTION: The introduction of Highly Active Antiretroviral Therapy (HAART) into clinical practice has dramatically changed the outcome of HIV-infected patients by prolonging their survival. The increase in life expectancy has...

Clinical outcomes of routine opt-out antenatal human immunodeficiency virus screening: A systematic review

2016

AIMS AND OBJECTIVES: To evaluate the clinical outcome of routine screening of human immunodeficiency virus in antenatal clinic settings. BACKGROUND: Despite the growing advances in human immunodeficiency virus management, nearly...

Pre-conception counselling for key cardiovascular conditions in Africa: Optimising pregnancy outcomes

2016

The World Health Organisation (WHO) supports pre-conception care (PCC) towards improving health and pregnancy outcomes. PPC entails a continuum of promotive, preventative and curative health and social interventions. PPC identifies...

Can trained lay providers perform HIV testing services? A review of national HIV testing policies

2017

BACKGROUND: Only an estimated 54% of people living with HIV are aware of their status. Despite progress scaling up HIV testing services (HTS), a testing gap remains. Delivery of HTS...

The impact of sharps injuries on student nurses: A systematic review

2016

AIMS AND OBJECTIVES: The purpose of this review was to discover the impact of sharps injuries in the student nurse population. BACKGROUND: Much is known and reported about sharps injuries...

Clinical management of adults and children with multidrug-resistant and extensively drug-resistant tuberculosis

2017

BACKGROUND: Globally there is a burgeoning epidemic of drug monoresistant tuberculosis (TB), multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB). Almost 20% of all TB strains worldwide are resistant to...

Maternal HCV infection is associated with intrauterine fetal growth disturbance: A meta-analysis of observational studies

2016

Since the evidence regarding the association between maternal hepatitis C virus (HCV) infection and impaired intrauterine fetal growth had not been conclusive, the aim of the present study was to...

The dynamic role of the IL-33/ST2 axis in chronic viral-infections: Alarming and adjuvanting the immune response

2016

UNLABELLED: Interleukin 33 (IL-33), a member of the IL-1 family, is constitutively expressed in epithelial and in endothelial cells at barrier sites, acting as a danger signal and adjuvanting the...

Eruptive nevi associated with medications (ENAMs)

2016

Eruptive melanocytic nevi have been reported in association with severe blistering diseases, renal transplantation, malignancy, AIDS, and medications. Eruptive nevi associated with medications have been reported with increasing frequency. Of...

The causative agents in infective endocarditis: A systematic review comprising 33,214 cases

2016

Infective endocarditis (IE) incidence remains high with considerable fatality rates; guidelines for prophylaxis against IE are currently under review in some settings which highlights the importance of maintaining up-to-date epidemiological...

HIV and orthopaedics: Musculoskeletal manifestations and outcomes

2016

Advances in combined antiretroviral therapy (cART) in recent years have transformed HIV infection into a chronic disease when treatment is available, increasing a patient’s life expectancy and the chances that...

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