SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Analysis of systematic reviews of medication adherence interventions for persons with HIV, 1996–2017

2019

This overview of reviews summarizes the evidence from systematic reviews (SR) on the effectiveness of antiretroviral therapy (ART) adherence interventions for people with HIV (PWH) and descriptively compares adherence interventions...

Vaginal ring acceptability and related preferences among women in low- and middle-income countries: A systematic review and narrative synthesis

2019

The vaginal ring (VR) is a female-initiated drug-delivery platform used for different indications, including HIV pre-exposure prophylaxis (PrEP). We conducted a systematic review of VR acceptability, values and preferences among...

Do combination HIV prevention programmes result in increased empowerment, inclusion and agency to demand equal rights for marginalised populations in low-income and middle-income countries? A systematic review

2019

Introduction: This systematic review aims to determine if combination HIV prevention programmes include outcome measures for empowerment, inclusion and agency to demand equal rights and measure the relationship between empowerment...

HIV epidemiology among female sex workers and their clients in the Middle East and North Africa: Systematic review, meta-analyses, and meta-regressions

2019

BACKGROUND: HIV epidemiology among female sex workers (FSWs) and their clients in the Middle East and North Africa (MENA) region is poorly understood. We addressed this gap through a comprehensive...

Intimate partner violence and pre-exposure prophylaxis (PrEP): A rapid review of current evidence for women’s HIV prevention

2019

Pre-exposure prophylaxis (PrEP) is a valued component of HIV prevention and increasing attention is focusing on women’s PrEP use. Common HIV prevention options (e.g., condoms) remain underused and fail to...

HIV self-testing in high-income settings: Acceptability, potential benefits and harms, issues related to linkage to care, interventions to increase HIV self-testing

2019

Key take-home messages HIV self-testing has the potential to increase rates of HIV testing and is acceptable to a range of populations in a variety of contexts. HIV self-testing is...

Efficacy and safety of raltegravir-based dual therapy in AIDS patients: A meta-analysis of randomized controlled trials

2019

Background: The life expectancy for HIV-infected individuals has improved dramatically because of improvements in antiretroviral therapy (ART). Today, a simplified two-drug regimen enhances adherence and treatment satisfaction by reducing adverse...

The risk of HIV among women after acquiring a sexually transmitted infection (STI) and considerations for their use of PrEP

2020

Key take-home messages A recent study in the U.S. found that most women who were diagnosed with HIV did not have a reported STI in the past. Another U.S. study...

ART adherence clubs in the Western Cape of South Africa: What does the sustainability framework tell us? A scoping literature review

2019

INTRODUCTION: In 2007, the antiretroviral therapy (ART) adherence club (AC) model was introduced to South Africa to combat some of the health system barriers to ART delivery, such as staff...

Stigma reduction interventions for children and adolescents in low- and middle-income countries: Systematic review of intervention strategies

2020

Stigmatisation and discrimination are common worldwide, and have profound negative impacts on health and quality of life. Research, albeit limited, has focused predominantly on adults. There is a paucity of...

Addressing minority stress and mental health among men who have sex with men (MSM) in China

2020

PURPOSE OF REVIEW: Men who have sex with men (MSM) in China experience elevated risks of mental health issues in comparison to the general population in China, which contribute to...

Crowdsourcing in health and medical research: A systematic review

2020

BACKGROUND: Crowdsourcing is used increasingly in health and medical research. Crowdsourcing is the process of aggregating crowd wisdom to solve a problem. The purpose of this systematic review is to...

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