SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The impact of location on implementation of HIV/STI prevention interventions among LGBTQ communities

2019

Key take-home messages The characteristics of a location, including segregation, community-level stigma, and infrastructural resources, may influence HIV service utilization and the HIV continuum of care among men who have...

A cross-jurisdictional review of HIV testing intervals for population groups at high risk of HIV infection

2019

Key take-home messages Most guidelines recommend at least annual HIV testing of population groups at high risk of HIV infection. These include: men who have sex with men, transgender women...

The association between marijuana use and HIV continuum of care outcomes: A systematic review

2019

PURPOSE OF REVIEW: Approximately 77% of HIV-infected adults report lifetime marijuana use. Given the high rates and social acceptability of marijuana use among HIV-infected individuals, it is important to gain...

Cardiovascular disease in the setting of human immunodeficiency virus infection

2018

BACKGROUND: Since the introduction of Antiretroviral Therapy (ART), the life expectancy and health quality for patients infected with Human Immunodeficiency Virus (HIV) have significantly improved. Nevertheless, as a result of...

Effect of Xpert MTB/RIF on clinical outcomes in routine care settings: Individual patient data meta-analysis

2019

BACKGROUND: Xpert MTB/RIF, the most widely used automated nucleic acid amplification test for tuberculosis, is available in more than 130 countries. Although diagnostic accuracy is well documented, anticipated improvements in...

Reducing HIV-related stigma and discrimination in healthcare settings: A systematic review of quantitative evidence

2019

INTRODUCTION: Stigma and discrimination (SAD) related to HIV compromise access and adherence to treatment and support programs among people living with HIV (PLHIV). The ambitious goal of ending the epidemic...

Peer-facilitated community-based interventions for adolescent health in low- and middle-income countries: A systematic review

2019

BACKGROUND: Adolescents aged 10-19 represent one sixth of the world’s population and have a high burden of morbidity, particularly in low-resource settings. We know little about the potential of community-based...

Pregabalin for neuropathic pain in adults

2019

BACKGROUND: This review updates part of an earlier Cochrane Review titled “Pregabalin for acute and chronic pain in adults”, and considers only neuropathic pain (pain from damage to nervous tissue)....

Progressive disseminated histoplasmosis in Latin America and the Caribbean in people receiving highly active antiretroviral therapy for HIV infection: A systematic review

2019

Histoplasmosis is the most clinically significant mycosis in Latin America; still it has been neglected in people with human immunodeficiency virus (HIV). There is limited information about its contribution to...

A systematic review with epidemiological update of male genital schistosomiasis (MGS): A call for integrated case management across the health system in sub-Saharan Africa

2018

Male genital schistosomiasis (MGS) is a gender specific manifestation of urogenital schistosomiasis (UGS) first described in 1911 by Madden in Egypt. Today, while affecting millions of men and boys worldwide,...

HIV, depression, and cognitive impairment in the era of effective antiretroviral therapy

2019

PURPOSE OF REVIEW: Mental health disorders, especially depression, are prevalent among people living with HIV (PLWH) and are associated with cognitive impairment (CI) among HIV-uninfected (HIV-) individuals. We conducted a...

Associations between anxiety and adherence to antiretroviral medications in low- and middle-income countries: A systematic review and meta-analysis

2019

Untreated mental health disorders among people living with HIV (PLHIV) may prevent low- and middle-income countries (LMICs) from achieving the UNAIDS 90-90-90 targets. Anxiety disorders may be associated with decreased...

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