Category Archives: Hepatitis B, C
Global epidemiology of HIV infection and related syndemics affecting transgender people
INTRODUCTION: Transgender populations have been underrepresented in HIV epidemiologic studies and consequently in HIV prevention, care, and treatment programs. Since 2012, there has been a dramatic increase in research focused...
Cancer risk factors among people living with HIV/AIDS in China: A systematic review and meta-analysis
Cancer is a leading cause of death among people living with HIV/AIDS (PLWHA). We conducted a systematic review and meta-analysis to evaluate prevalence of cancer risk factors among Chinese PLWHA...
HIV/HCV coinfection and the risk of cardiovascular disease: A meta-analysis
The emergence of improved antiretroviral therapy has increased the life expectancy of human immunodeficiency virus (HIV)-infected individuals, although there is an increased susceptibility to developing cardiovascular diseases (CVD). The risk...
Maternal HCV infection is associated with intrauterine fetal growth disturbance: A meta-analysis of observational studies
Since the evidence regarding the association between maternal hepatitis C virus (HCV) infection and impaired intrauterine fetal growth had not been conclusive, the aim of the present study was to...
The dynamic role of the IL-33/ST2 axis in chronic viral-infections: Alarming and adjuvanting the immune response
UNLABELLED: Interleukin 33 (IL-33), a member of the IL-1 family, is constitutively expressed in epithelial and in endothelial cells at barrier sites, acting as a danger signal and adjuvanting the...
HCV cure and reinfection among people with HIV/HCV coinfection and people who inject drugs
PURPOSE OF REVIEW: Highly effective, well-tolerated interferon-free direct-acting antivirals (DAA) have revolutionised hepatitis C virus (HCV) therapeutics, with the opportunity for broad treatment scale-up among marginalised or “high-risk” populations, including...
Effectiveness of needle and syringe programmes in people who inject drugs – An overview of systematic reviews
BACKGROUND: Needle and syringe programmes (NSP) are a critical component of harm reduction interventions among people who inject drugs (PWID). Our primary objective was to summarize the evidence on the...
Influence of vitamin D on liver fibrosis in chronic hepatitis C: A systematic review and meta-analysis of the pooled clinical trials data
AIM: To investigate the relationship between vitamin D and liver fibrosis in hepatitis C-monoinfected or hepatitis C virus (HCV)-human immunodeficiency virus (HIV) co-infected patients. METHODS: Pertinent studies were located by...
Seroprevalence and diagnosis of HIV, HBV, HCV and syphilis infections among blood donors
BACKGROUND: Blood transfusion is one of the most important therapeutic options of life-saving intervention for recipients who are in diseased or non-diseased conditions with severe blood loss. However, it is...
Incidence of hepatitis C in HIV positive and negative men who have sex with men 2000-2016: A systematic review and meta-analysis
BACKGROUND: There is a need for systematic reviews and meta-analyses to synthesize the epidemiology, and the riskfactors for hepatitis C virus (HCV) among HIV-coinfected and HIV negative men who have...