Category Archives: Tuberculosis
Incidence rate of mortality and its predictors among tuberculosis and human immunodeficiency virus coinfected patients on antiretroviral therapy in Ethiopia: Systematic review and meta-analysis
Background Tuberculosis (TB) is the leading cause of death among HIV-infected adults and children globally. Therefore, this study was aimed at determining the pooled mortality rate and its predictors among...
Prevalence and factors associated with viral non-suppression in people living with HIV receiving antiretroviral therapy in sub-Saharan Africa: A systematic review and meta-analysis
Despite advances in HIV treatment, the burden of viral non-suppression (VNS) remains a treatment success concern, particularly in Sub-Saharan African (SSA) countries. We determined the prevalence and factors associated with...
Prevalence, clinical features, and predictors of adrenal insufficiency in adults with tuberculosis or HIV: A systematic review and meta-analysis
BACKGROUND: Despite the high frequency of adrenal insufficiency (AI) in patients with tuberculosis or HIV, its diagnosis is often missed or delayed resulting in increased mortality. This systematic review and...
Risk factors for pulmonary tuberculosis recurrence, relapse and reinfection: A systematic review and meta-analysis
BACKGROUND: The rate of pulmonary tuberculosis (TB) recurrence is substantial. Identifying risk factors can support the development of prevention strategies. METHODS: We retrieved studies published between 1 January 1980 and...
Mortality of children and adolescents co-infected with tuberculosis and HIV: A systematic review and meta-analysis
Objective: Children and adolescents with HIV infection are well-known to face a heightened risk of tuberculosis. However, the exact mortality rates and temporal trends of those with HIV-TB co-infection remain unclear....
A systematic literature review of mathematical models for coinfections: Tuberculosis, malaria, and HIV/AIDS
Tuberculosis, malaria, and HIV are among the most lethal diseases, with AIDS (Acquired Immune Deficiency Syndrome) being a chronic and potentially life-threatening condition caused by the human immunodeficiency virus (HIV)....
Association of vitamin D with HIV infected individuals, TB infected individuals, and HIV-TB co-infected individuals: A systematic review and meta-analysis
Background Vitamin D deficiency (VDD) is a worldwide disease. VDD is also associated with an increased risk of HIV-related comorbidities and mortality, and patients have a tendency to develop active...
A systematic review and meta-analysis on the correlation between HIV infection and multidrug-resistance tuberculosis
Background The emergence of multidrug-resistant tuberculosis (MDR-TB) in HIV-positive people poses a significant challenge to international efforts to eradicate tuberculosis (TB). Many studies found conflicting results when examining the correlation...
A literature review on the adherence to screening guidelines for latent tuberculosis infection among persons living with HIV
Human immunodeficiency virus (HIV) infection increases the risk of reactivation of latent tuberculosis infection (LTBI). Although antiretroviral therapy decreases the progression of LTBI to tuberculosis disease (TBD), persons living with...
The incidence rate of tuberculosis and its associated factors among HIV-positive persons in Sub-Saharan Africa: A systematic review and meta-analysis
Background Tuberculosis, along with HIV, is the leading cause of mortality and morbidity globally. Despite the fact that several primary studies have been conducted on the incidence rate of tuberculosis...
Burden of tuberculosis among vulnerable populations worldwide: An overview of systematic reviews
Background Tuberculosis is a communicable disease of public health concern that inequitably impacts the most vulnerable populations worldwide. Vulnerable populations are those with a high risk for tuberculosis disease and...
