Category Archives: Co-infections
Prevalence of tuberculosis, hepatitis C virus, and HIV in homeless people: A systematic review and meta-analysis
BACKGROUND: 100 million people worldwide are homeless; rates of mortality and morbidity are high in this population. The contribution of infectious diseases to these adverse outcomes is uncertain. Accurate estimates...
Rifampicin plus pyrazinamide versus isoniazid for treating latent tuberculosis infection: A meta-analysis
SETTING: Six trials from Haiti, Mexico, the U.S.A., Brazil, Spain, Zambia and Hong Kong. OBJECTIVE: To evaluate the efficacy and safety of rifampicin plus pyrazinamide (RZ) vs. isoniazid (INH) for...
The role of coinfections in HIV epidemic trajectory and positive prevention: A systematic review and meta-analysis
OBJECTIVES: Recurrent or persistent coinfections may increase HIV viral load and, consequently, risk of HIV transmission, thus increasing HIV incidence. We evaluated the association between malaria, herpes simplex virus type...
Herpes simplex virus 2 infection increases HIV acquisition in men and women: Systematic review and meta-analysis of longitudinal studies
OBJECTIVE: To estimate the sex-specific effect of herpes simplex virus type 2 (HSV-2) on the acquisition of HIV infection. BACKGROUND: The increased number of longitudinal studies available since the last...
A meta-analysis of the efficacy of HIV/AIDS prevention interventions in Asia, 1995-2009
The HIV/AIDS epidemic continues to grow in pockets across Asia, despite early successes at curtailing its spread in countries like Thailand. Recent evidence documents dramatic increases in incidence among risk...
Meta-analysis of prevention and treatment of toxoplasmic encephalitis in HIV-infected patients
Toxoplasmic encephalitis (TE) is one of the most common central nervous system (CNS) opportunistic infections in HIV-infected patients. It can be prevented and treated through drug regimen. However, drugs have...
Influenza Vaccination for Immunocompromised Patients: Systematic Review and Meta-analysis by Etiology
Many national guidelines recommend annual influenza vaccination of immunocompromised patients, although the decision to vaccinate is usually at clinical discretion. We conducted a systematic review and meta-analyses to assess the...
Evidence behind the WHO guidelines: Hospital Care for Children: The usefulness of azole prophylaxis against cryptococcal meningitis in HIV-positive children
The World Health Organization has produced guidelines for the management of common illnesses in hospitals with limited resources. This series reviews the scientific evidence behind WHO’s recommendations. The WHO guidelines...
Multifocal Epstein-Barr Virus-associated smooth muscle tumor in adults with AIDS: Case report and review of the literature
Objectives: The aim of this study was to provide a systematic review of Epstein-Barr virus-associated smooth muscle tumors (EBV-SMT) in human immunodeficiency virus (HIV)-infected adults, focusing on clinical and histopathologic...
Community empowerment among female sex workers is an effective HIV prevention intervention: A systematic review of the peer-reviewed evidence from low- and middle-income countries
We conducted a systematic review and meta-analysis of community empowerment interventions for HIV prevention among sex workers in low- and middle-income countries from 1990–2010. Two coders abstracted data using standardized...
