Category Archives: Co-infections
Prevalence of sexually transmitted infections and bacterial vaginosis among women in sub-Saharan Africa: An individual participant data meta-analysis of 18 HIV prevention studies
BACKGROUND: Estimates of sexually transmitted infection (STI) prevalence are essential for efforts to prevent and control STIs. Few large STI prevalence studies exist, especially for low- and middle-income countries (LMICs)....
High prevalence of hepatitis B infections in Burkina Faso (1996-2017): A systematic review with meta-analysis of epidemiological studies
BACKGROUND: Hepatitis B virus (HBV) infection was long considered an important public health concern in Burkina Faso and still represents a major cause of liver cancer and cirrhosis in the...
Pharmacokinetics of efavirenz in patients on antituberculosis treatment in high HIV and tuberculosis burden countries: A systematic review
AIMS: Efavirenz (EFV) and Rifampicin-Isoniazid (RH) are cornerstone drugs in HIV-tuberculosis (TB) co-infection treatment but with complex drug interactions, efficacy and safety challenges. We reviewed recent data on EFV and...
Incidence and risk factors for prediabetes and diabetes mellitus among HIV-infected adults on antiretroviral therapy: A systematic review and meta-analysis
OBJECTIVE: To summarize evidence on the rates and drivers of progression from normoglycemia to prediabetes and/or diabetes mellitus (hereafter “diabetes”) in antiretroviral treatment (ART)-exposed HIV-infected people. METHODS: We searched EMBASE,...
Neurological sequelae of adult meningitis in Africa: A systematic literature review
The high human immunodeficiency virus (HIV) prevalence in sub-Saharan Africa has markedly changed the epidemiology and presentation of adult meningitis. We conducted a systematic review using PubMed, Embase, Ovid, CENTRAL,...
HIV-positive women have higher risk of HPV infection, precancerous lesions, and cervical cancer: A systematic review and meta-analysis
OBJECTIVES: HIV-positive women have higher human papillomavirus (HPV) prevalence and cervical cancer (CC) incidence than HIV-negative women, partly due to HIV’s modifying effect on HPV pathogenesis. We synthesized the literature...
CD4 count and tuberculosis risk in HIV-positive adults not on ART: A systematic review and meta-analysis
Background: CD4 cell count in adults with human immunodeficiency virus (HIV) infection (PLHIV) not receiving antiretroviral therapy (ART) influences tuberculosis (TB) risk. Despite widespread use in models informing resource allocation,...
Is an endoscopic examination associated with transfusion-transmissible infections? A systematic review and meta-analysis
BACKGROUND: The purpose of a donor medical questionnaire is to identify the blood donor’s history relative to the current known blood-safety risks. A temporary deferral from blood donation after an...
Mortality and its predictors among HIV infected patients taking antiretroviral treatment in Ethiopia: A systematic review
Background: Even though the benefit of antiretroviral therapy (ART) is well established, there is a regional variation in the extent of its benefit. The aim of this review is to...
Review of toxoplasmosis in Morocco: Seroprevalence and risk factors for toxoplasma infection among pregnant women and HIV- infected patients
Toxoplasmosis is a disease caused by a protozoal parasite: Toxoplasma gondii. This infection can cause severe illness when the organism is contracted congenitally or when it is reactivated in immunosuppressed...
Estimating the prevalence of positive tuberculin skin test reactions in general population and high-risk groups: A meta-analysis
Results of tuberculin skin test (TST) surveys among different populations have been reported in many studies as a method for detecting primary Mycobacterium tuberculosis infection. Combining these results provides reliable...
