Category Archives: Co-infections
HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality
BACKGROUND: International human migration has been rapidly growing. Migrants coming from low and middle income countries continue to be considerably vulnerable and at higher risk for infectious diseases, namely HIV...
Antiretroviral therapy in HIV infected children with tuberculosis: A systematic review
BACKGROUND: Tuberculosis is the major cause of mortality in HIV-infected children globally. Current guidelines about the management of antiretroviral therapy in children with tuberculosis are based on a limited number...
Does pre-exposure prophylaxis (PrEP) for HIV prevention in men who have sex with men (MSM) change risk behavior? A systematic review
BACKGROUND: Pre-exposure prophylaxis (PrEP) for HIV has been available since 2012. Even so, PrEP has not been widely accepted among healthcare providers and MSM some of whom are convinced that...
Oral candidiasis among African human immunodeficiency virus-infected individuals: 10 years of systematic review and meta-analysis from sub-Saharan Africa
Oral candidiasis (OC) is the most common opportunistic fungal infection among immunocompromised individuals. This systematic review and meta-analysis reports on the contribution of non-albicans Candida species in causing OC among...
Cancer risk factors among people living with HIV/AIDS in China: A systematic review and meta-analysis
Cancer is a leading cause of death among people living with HIV/AIDS (PLWHA). We conducted a systematic review and meta-analysis to evaluate prevalence of cancer risk factors among Chinese PLWHA...
HIV/HCV coinfection and the risk of cardiovascular disease: A meta-analysis
The emergence of improved antiretroviral therapy has increased the life expectancy of human immunodeficiency virus (HIV)-infected individuals, although there is an increased susceptibility to developing cardiovascular diseases (CVD). The risk...
Anogenital warts and other HPV-associated anogenital lesions in the HIV-positive patient: A systematic review and meta-analysis of the efficacy and safety of interventions assessed in controlled clinical trials
OBJECTIVES: Anogenital warts (AGW, condylomata acuminata) and intraepithelial neoplasia (IEN) do not only impact health and social well-being, they are also associated with considerable costs for the healthcare systems. Immunocompromised...
Does maternal HSV-2 coinfection increase mother-to-child transmission of HIV? A systematic review
BACKGROUND: Reducing HIV mother-to-child transmission (MTCT) is critical to ending the HIV pandemic. Reports suggest that herpes simplex virus-2 (HSV-2), a common coinfection in HIV-infected individuals, is associated with increased...
Accuracy of the interferon-gamma release assay for the diagnosis of active tuberculosis among HIV-seropositive individuals: A systematic review and meta-analysis
BACKGROUND: Although the interferon-gamma release assay (IGRA) has become a widely accepted means for the diagnosis of latent tuberculosis infection (LTBI), the role of the IGRA in diagnosing active tuberculosis...
Initiation and completion rates for latent tuberculosis infection treatment: A systematic review
BACKGROUND: Control of latent tuberculosis infection (LTBI) is an important step towards tuberculosis elimination. Preventive treatment will prevent the development of disease in most cases diagnosed with LTBI. However, low...
