Category Archives: Co-infections

Valganciclovir: An advance in cytomegalovirus therapeutics

2002

OBJECTIVE: To review the pharmacology, pharmacokinetics, and preliminary clinical data for valganciclovir, a new oral agent for the therapy of cytomegalovirus (CMV) retinitis. DATA SOURCES: Relevant literature was extracted via...

Interventions for the prevention and management of oropharyngeal candidiasis associated with HIV infection in adults and children

2010

BACKGROUND: Oral candidiasis (OC) associated with human immunodeficiency virus (HIV) infection occurs commonly and recurs frequently, often presenting as an initial manifestation of the disease. Left untreated, these lesions contribute...

Flu and pneumococcal immunisations in HIV-infected children: Methodological quality of current recommendations

2011

OBJECTIVE: To assess the quality of guidelines, consensus statements and systematic reviews on flu and pneumococcal immunisations in HIV-infected children. METHOD: The authors screened PubMed and Embase databases until the...

Interventions for the prevention of mycobacterium avium complex in adults and children with HIV

2013

BACKGROUND: Mycobacterium avium complex (MAC) infection is a common complication of advanced acquired immunodeficiency syndrome (AIDS) disease and is an independent predictor of mortality and shortened survival. OBJECTIVES: To determine...

The effect of genital tract infections on HIV-1 shedding in the genital tract: A systematic review and meta-analysis

2008

This article reviews the effect of genital tract infections and associated clinical conditions on the detection and concentration of HIV-1 shedding in the genital tract. A search of the PubMed,...

The effectiveness of behavioural and psychosocial HIV/STI prevention interventions for MSM in Europe: A systematic review

2009

Given the need of programme planners and policy makers for descriptions of specific interventions and quantitative estimates of intervention effects to make informed decisions concerning prevention funding and research, there...

Management of toxoplasmic encephalitis in HIV-infected adults (with an emphasis on resource-poor settings)

2006

BACKGROUND: Cerebral toxoplasmosis or toxoplasmic meningoencephalitis (hereafter referred to as TE) was one of the first opportunistic infections to be described in human immunodeficiency virus (HIV) -infected patients. Treatment of...

Impact of hepatitis C co-infection on response to antiretroviral treatment

2012

The MONET study, comparing darunavir/ritonavir-based triple therapy and monotherapy, has found higher risk of failure in patients with positive HCV serology, but the effects of HCV co-infection on the efficacy...

The impact of hepatitis C virus coinfection on HIV-related kidney disease: A systematic review and meta-analysis

2008

BACKGROUND: In the era of antiretroviral therapy, non-AIDS complications such as kidney disease are important contributors to morbidity and mortality. OBJECTIVE: To estimate the impact of hepatitis C coinfection on...

Peginterferon alfa-2a is superior to peginterferon alfa-2b in the treatment of naïve patients with hepatitis C virus infection: Meta-analysis of randomized controlled trials.

2011

BACKGROUND: Pegylated interferon (PEGIFN) and ribavirin combination is the standard of care for the treatment of chronic hepatitis C virus (HCV) infection. Studies comparing the efficacy and safety of PEGIFN...

Socio-demographic characteristics and behavioral risk factors of female sex workers in sub-saharan Africa: A systematic review

2012

Sex work remains an important contributor to HIV transmission within early, advanced and regressing epidemics in sub-Saharan Africa, but its social and behavioral underpinnings remain poorly understood, limiting the impact...

Meta-analysis: Prevalence of HIV infection and syphilis among MSM in China

2009

OBJECTIVES: The prevalence of HIV/AIDS and other sexually transmitted diseases is rapidly rising among men who have sex with men (MSM) in China. The aim is to systematically review the...

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