Category Archives: Co-infections
Effects of interferon-alpha treatment on the incidence of hyperglycemia in chronic hepatitis c patients: A systematic review and meta-analysis
Background: There is a significant association between effects of interferon-alpha treatment and the risk of developing hyperglycemia in patients with chronic hepatitis C virus (HCV) infection. The objective of this...
Treatment of syphilis in HIV-infected subjects: A systematic review of the literature
Background: The optimal antimicrobial regimen to treat syphilis in HIV-infected subjects remains controversial. Objective To systematically assess the literature for studies evaluating syphilis treatment regimens in this population. Methods: Two...
Interferon-γ release assays for active pulmonary tuberculosis diagnosis in adults in low-and middle-income countries: Systematic review and meta-analysis
Background. The diagnostic value of interferon- release assays (IGRAs) for active tuberculosis in low- and middle-income countries is unclear. Methods. We searched multiple databases for studies published through May 2010...
Interferon-gamma release assays for the diagnosis of tuberculosis and tuberculosis infection in HIV-infected adults: A systematic review and meta-analysis
BACKGROUND: Despite the widespread use of interferon-gamma release assays (IGRAs), their role in diagnosing tuberculosis and targeting preventive therapy in HIV-infected patients remains unclear. We conducted a comprehensive systematic review...
Factors associated with patient and health care system delay in diagnosis and treatment for TB in sub-Saharan African countries with high burdens of TB and HIV
OBJECTIVE: To identify factors causing delayed diagnosis and treatment for tuberculosis in high tuberculosis (TB)/HIV burden African countries. METHODS: We searched Ovid Medline, CINAHL, PsychInfo, Scopus and Sabinet-South African journals...
Yield of HIV-associated tuberculosis during intensified case finding in resource-limited settings: A systematic review and meta-analysis
Intensified case finding is the regular screening for evidence of tuberculosis in people infected with HIV, at high risk of HIV, or living in congregate settings. We systematically reviewed studies...
Prevalence of sexually transmitted co-infections in people living with HIV/AIDS: Systematic review with implications for using HIV treatments for prevention.
Sexually transmitted co-infections increase HIV infectiousness through local inflammatory processes. The prevalence of STI among people living with HIV/AIDS has implications for containing the spread of HIV in general and...
Discontinuation of Pneumocystis jirovecii pneumonia prophylaxis with CD4 count <200 cells/mul and virologic suppression: A systematic review
Background: HIV viral load (VL) is currently not part of the criteria for Pneumocystis jirovecii pneumonia (PCP) prophylaxis discontinuation, but suppression of plasma viremia with antiretroviral therapy may allow for...
