Category Archives: Cardiovascular
Risk of death and readmission among individuals with heart failure and HIV: A systematic review and meta-analysis
The association between human immunodeficiency virus (HIV) status and readmissions and death outcomes in patients with established heart failure (HF) remains unclear. We conducted a systematic search of PubMed, EMBASE,...
Prevalence of obesity, hypertension and diabetes among people living with HIV in South Africa: A systematic review and meta-analysis
Background HIV has become a manageable chronic condition due to the success and scale-up of antiretroviral therapy (ART). Globally, South Africa has the highest number of people living with HIV...
Cardiovascular challenges in the era of antiretroviral therapy for AIDS/ HIV: A comprehensive review of research advancements, pathophysiological insights, and future directions
Cardiovascular disease, particularly coronary heart disease, is becoming more common among those living with HIV. Individuals with HIV face an increased susceptibility to myocardial infarction, also known as a heart...
The impact of contemporary antiretroviral drugs on atherosclerosis and its complications in people living with HIV: A systematic review
With thWith the advent of modern antiretroviral therapy (ART), human immunodeficiency virus (HIV) infection has been modified into a chronic manageable condition, prolonging the lifespan of people living with HIV...
Systematic review on cumulative HIV viraemia among people living with HIV receiving antiretroviral treatment and its association with mortality and morbidity
BACKGROUND: We performed a systematic review to generate evidence on the association between cumulative human immunodeficiency virus (HIV) viraemia and health outcomes. METHODS: Quantitative studies reporting on HIV cumulative viraemia...
The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Non-communicable diseases (NCDs) are increasing among people living with HIV (PLHIV), especially in Sub-Saharan Africa (SSA). We determined the prevalence of NCDs and NCD risk factors among PLHIV in...
Prevalence and impact of HIV infections in patients with rheumatic heart disease: A systematic review and meta-analysis
Socioeconomic factors such as poor health and poor nutrition in low- and middle-income countries (LMICs) may favour inflammatory reactions, thus contributing to the recurrence of rheumatic fever (RF) and thereby...
The risk of new heart failure associated with protease inhibitor: Systematic scoping review
BACKGROUND: Protease inhibitors (PIs) have contributed to the long-term survival of persons with human immunodeficiency virus (PHIV). While there is a concern linking protease inhibitors to an increased risk of...
A systematic review and meta-analysis on the impact of statin treatment in HIV patients on antiretroviral therapy
The rate of new human immunodeficiency virus (HIV) infections globally is alarming. Although antiretroviral therapy (ART) improves the quality of life among this group of patients, ARTs are associated with...
Prevalence and incidence of stroke among people living with HIV: A systematic review and meta-analysis
Objective: We aimed to obtain more precise estimates of stroke to address the wide variation of stroke burden among people with HIV (PWH) in different clinical settings. Design: Systematic review and meta-analysis....
