Category Archives: Other
Prevalence, severity, and duration of thrombocytopenia among HIV patients in the era of highly active antiretroviral therapy
Thrombocytopenia is a clinically relevant outcome in HIV. However, the epidemiology of this condition, including frequency, severity, and duration, has not been well-characterized in the era of highly active antiretroviral...
Bone mineral density in HIV-infected women taking antiretroviral therapy: A systematic review
There is a high prevalence of osteoporosis in HIV-infected patients. Initially described in HIV-positive men, studies have also demonstrated a high prevalence of osteoporosis in HIV-infected women. It would appear...
Clinical utility of biomarkers of endothelial activation and coagulation for prognosis in HIV infection: A systematic review
INTRODUCTION: HIV infection is associated with vascular dysfunction and adverse cardiovascular outcomes. Our objective was to review the evidence regarding the clinical utility of endothelial activation and coagulation biomarkers for...
Infections and inflammatory diseases as risk factors for venous thrombosis. A systematic review
Inflammation and venous thrombosis are intertwined. Only in the recent 15 years clinical epidemiological studies have focussed on inflammatory or infectious diseases as risk factors for venous thrombosis. Although a...
Cardiac dysfunction in pauci symptomatic human immunodeficiency virus patients: A meta-analysis in the highly active antiretroviral therapy era
AIMS: Human immunodeficiency virus infection (HIV) has been associated with cardiac dysfunction that, if present, can negatively affect morbidity and mortality of HIV-infected patients. Unfortunately, many of the studies on...
Complementary and alternative medicine in the management of pain, dyspnea, and nausea and vomiting near the end of life. A systematic review
To review the evidence for efficacy of complementary and alternative medicine (CAM) modalities in treating pain, dyspnea, and nausea and vomiting in patients near the end of life, original articles...
A meta-analysis of six placebo-controlled trials of thiazolidinedione therapy for HIV lipoatrophy
Objective: To determine the impact of thiazolidinediones (TZD) on changes in limb fat mass in HIV-infected individuals, particularly in those not receiving a thymidine analogue.Methods: Individual patient data from placebo-controlled,...
Effectiveness of aerobic exercise in adults living with HIV/AIDS: Systematic review
PURPOSE: The objective of this systematic review was to examine the effectiveness and safety of aerobic exercise interventions on immunological/virological, cardiopulmonary, and psychological outcomes in adults living with HIV/AIDS. METHODS:...
Kidney and liver organ transplantation in persons with human immunodeficiency virus: An evidence-based analysis
The objective of this analysis is to determine the effectiveness of solid organ transplantation in persons with end stage organ failure (ESOF) and human immunodeficiency virus (HIV+) Clinical Need: Condition...
Lipid profiles in HIV-infected adults receiving atazanavir and atazanavir/ritonavir: Systematic review and meta-analysis of randomized controlled trials
OBJECTIVES: To compare lipid profiles in HIV-infected adults receiving atazanavir-based regimens. METHODS: We conducted a systematic review of randomized controlled trials (RCTs) comparing atazanavir or atazanavir/ritonavir with a comparator and...
Efficacy and safety of cesarean delivery for prevention of mother-to-child transmission of HIV-1
BACKGROUND: Cesarean section before labor and before ruptured membranes (“elective cesarean section”, or ECS) has been introduced as an intervention for the prevention of mother-to-child transmission (MTCT) of HIV-1. The...
