Category Archives: Co-morbidities

Anemia and thrombocytopenia in people living with HIV/AIDS: A narrative literature review

2021

Hematologic changes are frequent complications in people living with HIV/AIDS (PLWHA). Anemia and thrombocytopenia are the most frequent multifactorial hematologic abnormalities and are associated with a low quality of life...

Role of brain arterial remodeling in HIV-associated cerebrovascular outcomes

2021

As the life expectancy of people living with HIV (PLWH) on combination antiretroviral therapy (cART) increases, so does morbidity from cerebrovascular disease and neurocognitive disorders. Brain arterial remodeling stands out...

Prevalence of high-risk HPV genotypes in sub-Saharan Africa based on human immunodeficiency virus status: A 20-year systematic review

2021

This review assessed the rate of high-risk Human papillomavirus (HPV) infection among women living in sub-Saharan Africa. It also determined the prevalence of high-risk HPV (hrHPV) among human immunodeficiency virus...

Toxic metals and non-communicable diseases in HIV population: A systematic review

2021

Background and Objectives: HIV has been a serious global health concern since its discovery, with about 37.9 million people living with HIV worldwide as of 2018. Sub-Saharan Africa (SSA) accounts...

Association between HIV infection and hypertension: A global systematic review and meta-analysis of cross-sectional studies

2021

Background: Improved access to effective antiretroviral therapy has meant that people living with HIV (PLHIV) are surviving to older ages. However, PLHIV may be ageing differently to HIV-negative individuals, with...

HIV and COVID-19: Lessons from HIV and STI harm reduction strategies

2021

PURPOSE OF REVIEW: This review highlights the intersection of the COVID-19, HIV, and STI pandemics and examines how harm reduction strategies can be applied broadly to controlling a pandemic. RECENT...

Lights and shadows of microbiota modulation and cardiovascular risk in HIV patients

2021

Human immunodeficiency virus (HIV) infection is associated with premature aging and the development of aging-related comorbidities, such as cardiovascular disease (CVD). Gut microbiota (GM) disturbance is involved in these comorbidities...

Kidney transplantation in HIV-positive patients: Current practice and management strategies

2021

BACKGROUND: HIV-positive patients had been successfully transplanted for the last 15 y and the donor pool had successfully been expanded to also include HIV-positive donors. METHODS: We aimed to evaluate...

Association of HIV infection and antiretroviral therapy With arterial stiffness: A systematic review and meta-analysis

2021

Incidence of cardiovascular disease in people living with HIV has increased as overall survival has improved because of combination antiretroviral therapy (cART). Arterial stiffness is a composite indicator of cardiovascular...

Risk of hepatocellular carcinoma in hepatitis B and D virus co-infected patients: A systematic review and meta-analysis of longitudinal studies

2021

Hepatitis D virus (HDV) infection causes a severe chronic viral hepatitis with accelerated development of liver cirrhosis and decompensation, but whether it further increases the risk of hepatocellular carcinoma (HCC)...

Course of disease and clinical outcome of infective endocarditis in HIV-infected individuals: A systematic review and meta-analysis

2020

Infective endocarditis (IE) causes substantial morbidity and mortality if untreated. The clinical course of IE might be different in HIV-positive patients as a result of immune dysfunction. This systematic review...

Cardiovascular risks associated with protease inhibitors for the treatment of HIV

2021

Introduction: Cumulative use of some first-generation protease inhibitors has been associated with higher rates of dyslipidemia and increased risk of cardiovascular disease. The protease inhibitors most commonly in use are...

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