Category Archives: Co-morbidities
Prevalence of HIV-seropositivity and associated impact on mortality among injured patients from low-and middle-income countries: A systematic review and meta-analysis
BACKGROUND: Although HIV and injury contribute substantially to disease burdens in low-and middle-income countries (LMIC), their intersection is poorly characterized. OBJECTIVE: This systematic review assessed the prevalence and associated mortality...
Children with HIV: A scoping review of auditory processing skills
INTRODUCTION: Auditory processing disorders can negatively affect academic performance in children. They can result from a number of aetiologies, including the human immunodeficiency virus (HIV). Although studies in paediatrics are...
Abnormal QTc syndrome in HIV-infected patients: A systematic review of prevalence and risk factors
BACKGROUND: The purpose of this review is to critically analyze data regarding the prevalence and risk factors for developing a prolonged QTc interval and subsequent sudden cardiac death (SCD) in...
Risk of myocardial infarction among people living with HIV: An updated systematic review and meta-analysis
OBJECTIVE: Cardiovascular disease (CVD) is one of the leading non-AIDS-defining causes of death among HIV-positive (HIV+) individuals. However, the evidence surrounding specific components of CVD risk remains inconclusive. We conducted...
Human immunodeficiency virus and risk of pre-eclampsia and eclampsia in pregnant women: A meta-analysis on cohort studies
Maternal HIV infection is related to several perinatal adverse outcomes. This study is aimed at establishing whether maternal HIV infection is associated with the development of pre-eclampsia (PE) and eclampsia....
The effect of HIV infection, antiretroviral therapy on carotid intima-media thickness: A systematic review and meta-analysis
AIMS: We performed a systematic review and meta-analysis on the effect of HIV infection and antiretroviral therapy (ART) on carotid intima-media thickness (cIMT) to elucidate the role of HIV infection...
Combined antiretroviral therapy for HIV and the risk of hypertensive disorders of pregnancy: A systematic review
OBJECTIVE: To assess if there is a relationship between use of combined antiretroviral therapy among pregnant women living with HIV and hypertensive disorders of pregnancy (HDP). DESIGN: Due to the...
Heart failure among people with HIV: Evolving risks, mechanisms, and preventive considerations
PURPOSE: People with HIV (PHIV) with access to modern antiretroviral therapy (ART) face a two-fold increased risk of heart failure as compared with non-HIV-infected individuals. The purpose of this review...
Tenofovir-associated kidney disease in Africans: A systematic review
BACKGROUND: Data on chronic kidney disease development in HIV infection is important towards building a comprehensive knowledge of HIV, ageing and polypharmacy in Africa. Several previous studies on tenofovir-associated kidney...