Category Archives: Co-morbidities

Human immunodeficiency virus and risk of pre-eclampsia and eclampsia in pregnant women: A meta-analysis on cohort studies

2019

Maternal HIV infection is related to several perinatal adverse outcomes. This study is aimed at establishing whether maternal HIV infection is associated with the development of pre-eclampsia (PE) and eclampsia....

The effect of HIV infection, antiretroviral therapy on carotid intima-media thickness: A systematic review and meta-analysis

2019

AIMS: We performed a systematic review and meta-analysis on the effect of HIV infection and antiretroviral therapy (ART) on carotid intima-media thickness (cIMT) to elucidate the role of HIV infection...

Combined antiretroviral therapy for HIV and the risk of hypertensive disorders of pregnancy: A systematic review

2019

OBJECTIVE: To assess if there is a relationship between use of combined antiretroviral therapy among pregnant women living with HIV and hypertensive disorders of pregnancy (HDP). DESIGN: Due to the...

Effects of malaria/helminthic coinfections on cervical cancer progression among sub Saharan African women on highly active antiretroviral therapy: A scoping review

2019

In Africa, the HIV prevalence in rural areas has begun to reach levels estimated within urban settings, where women are also more at risk for both malaria and intestinal parasitic...

The accuracy of anal swab-based tests to detect high-grade anal intraepithelial neoplasia in HIV-infected patients: A systematic review and meta-analysis

2019

Background: The incidence of high-risk human papillomavirus (HR-HPV)-induced anal cancer is increasingly problematic among HIV-positive patients. Anal cancer is preceded by precursor lesions, anal intraepithelial neoplasia (AIN). AIN detection requires...

Precancerous cervical lesion among HIV-positive women in sub-Saharan Africa: A systematic review and meta-analysis

2019

In sub-Saharan Africa, cervical cancer is an intersecting epidemic with HIV and it is the second most common cause of cancer-related deaths in women. Therefore, this study was aimed to...

Patho-immune mechanisms of hypertension in HIV: A systematic and thematic review

2019

PURPOSE OF REVIEW: To systematically review recent findings on the role of immune cell activation in the pathogenesis of hypertension in people living with HIV (PLWH) and compare studies from...

Pulmonary hypertension in the global population of adolescents and adults living with HIV: A systematic review and meta-analysis

2019

A systematic review and meta-analysis was conducted to estimate the prevalence of PH in adolescents and adults living with HIV at the global level. PubMed, EMBASE, Web of Science, and...

Gestational diabetes mellitus in HIV-infected pregnant women: A systematic review and meta-analysis

2019

BACKGROUND: Impaired glucose metabolism during pregnancy can result in a significant adverse pregnancy-outcomes. Previous studies have reported the contribution of ART to the impaired glucose tolerance and gestational diabetes mellitus...

Tenofovir-associated kidney disease in Africans: A systematic review

2019

BACKGROUND: Data on chronic kidney disease development in HIV infection is important towards building a comprehensive knowledge of HIV, ageing and polypharmacy in Africa. Several previous studies on tenofovir-associated kidney...

Gynecologic cancer in HIV-positive women: A systematic review and meta-analysis

2019

BACKGROUND: While there is a significant body of literature on cervical cancer in HIV-positive women, little is known about other gynecologic cancers in this population. OBJECTIVE: The objective of this...

Managing pharmacotherapy in people living with HIV and concomitant malignancy

2019

OBJECTIVE: To describe data with selected malignancies in people living with HIV (PLWH) and HIV in individuals affected by both conditions and to summarize drug-drug interactions (DDIs) with clinical recommendations...

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