Category Archives: Co-morbidities

Immune checkpoint inhibitor therapy for cancer patients infected with HIV: A systematic review

2020

BACKGROUND: Immune checkpoint inhibitor (ICI) therapy represents a breakthrough in cancer treatment. However, clinical trials of ICI have usually excluded people living with HIV (PLWH). The efficacy and safety data...

Aging with HIV

2019

PURPOSE OF REVIEW: This review points out unmet medical needs and open research questions of older adults living with HIV. Starting from the definition of aging in HIV, it explores...

QT prolongation in HIV-positive patients: Review article

2019

INTRODUCTION: Antiretrovirals have immensely increased the average life expectancy of HIV-positive patients. However, the incidence of QT interval prolongation and other arrhythmias has also increased. METHODS: Pubmed and Google Scholar...

Effect of omega-3 polyunsaturated fatty acids treatment on lipid pattern of HIV patients: A meta-analysis of randomized clinical trials

2020

Even though omega-3 polyunsaturated fatty acids (PUFAs) seem to be effective in the treatment of human immunodeficiency virus (HIV)-associated dyslipidemia, their impact is still debated. For this reason, our aim...

Global burden of hypertension among people living with HIV in the era of increased life expectancy: A systematic review and meta-analysis

2020

BACKGROUND: Although HIV infection and antiretroviral therapy (ART) increase the risk for hypertension in people living with HIV (PLHIV), the global and regional burden of hypertension in PLHIV is not...

The safety and efficacy of immune checkpoint inhibitors in patients with advanced cancers and pre-existing chronic viral infections (Hepatitis B/C, HIV): A review of the available evidence

2020

The treatment paradigm of several cancers has dramatically changed in recent years with the introduction of immunotherapy. Most oncology trials involving immune checkpoint inhibitors (ICIPs) have routinely excluded patients with...

Difference in toxicity between HIV-positive and HIV-negative patients with squamous-cell cancer of the anal canal treated with concomitant radio-chemotherapy

2020

Background: The incidence of squamous cell carcinoma of the anal canal has been increasing over the last 30 years. HIV has been found to be a risk factor for the...

The safety and efficacy of marijuana in persons living with HIV

2019

The prevalence of the use of marijuana throughout the world is substantial. In light of ongoing increases in accessibility to marijuana, safety and efficacy must be established to guide recommendations...

Stroke and systemic thromboembolism prevention in people living With human immunodeficiency virus with atrial fibrillation: A review of its implications for clinical practice

2019

In the last few decades, types of diseases affecting people living with human immunodeficiency virus (PLHIV) have shifted as the population ages, with cardiovascular disease becoming a leading cause of...

Sarcopenia in people living with the Human Immunodeficiency Virus: A systematic review and meta-analysis

2020

People living with HIV (PLHIV) experience greater loss of muscle mass and function than people without HIV. However, HIV is not routinely recognized as a sarcopenia risk factor outside of...

Prevention of cardiovascular disease for historically marginalized racial and ethnic groups living with HIV: A narrative review of the literature

2020

Despite developments to improve health in the United States, racial and ethnic disparities persist. These disparities have profound impact on the wellbeing of historically marginalized racial and ethnic groups. This...

Nature and extent of hearing loss in HIV-infected children: A scoping review

2020

INTRODUCTION: Antiretroviral therapy (ART) has had a major impact on life expectancy from HIV as many people now live with it as a chronic disease. Chronic HIV has been associated...

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