Category Archives: Co-morbidities

Reduced bone mineral density in human immunodeficiency virus-infected individuals: A meta-analysis of its prevalence and risk factors

2017

A meta-analysis was conducted to evaluate the prevalence of osteopenia/osteoporosis in human immunodeficiency virus (HIV)-infected individuals. The prevalence of osteopenia/osteoporosis in HIV-infected and antiretroviral therapy (ART)-treated individuals was significantly higher...

Prevalence and etiologies of pulmonary hypertension in Africa: A systematic review and meta-analysis

2017

BACKGROUND: Despite the recent increasing worldwide attention towards pulmonary hypertension (PH), its epidemiology remains poorly described in Africa. Accordingly, we performed a systematic review and meta-analysis of PH prevalence, incidence...

Breast cancer and HIV: A South African perspective and a critical review of the literature

2017

BACKGROUND: The diagnosis of breast cancer and concurrent HIV in South Africa is common. The limited current evidence on this subject suggests that the patients thus afflicted appear to be...

Cervical cancer prevention and treatment research in Africa: A systematic review from a public health perspective

2016

BACKGROUND: Women living in Africa experience the highest burden of cervical cancer. Research and investment to improve vaccination, screening, and treatment efforts are critically needed. We systematically reviewed and characterized...

Renal manifestations of HIV during the antiretroviral era in South Africa: A systematic scoping review

2017

BACKGROUND: It is estimated that 650,000 patients may develop human immunodeficiency virus (HIV)-related renal disease in South Africa. South Africa has recently adopted WHO policy, stipulating that all HIV-infected patients...

Global epidemiology of human herpesvirus 8 in men who have sex with men: A systematic review and meta-analysis

2017

Men who have sex with men (MSM) were highly vulnerable to HIV/AIDS and Human herpes virus 8 (HHV8), while the epidemiologic features of HHV8 among MSM remain obscure. We therefore...

Association between the use of protease inhibitors in highly active antiretroviral therapy and incidence of diabetes mellitus and/or metabolic syndrome in HIV-infected patients: A systematic review and meta-analysis

2017

This systematic review and meta-analysis tries to determine whether there is an association between the use of protease inhibitors (PIs) and the incidence of diabetes mellitus (DM) and/or metabolic syndrome...

Evidence-based review of statin use in patients with HIV on antiretroviral therapy

2017

INTRODUCTION: As a result of improved safe and effective therapeutic options for human immunodeficiency virus (HIV), life expectancy of those living with HIV is increasing leading to new challenges (e.g.,...

Effectiveness of n-3 fatty acids in the treatment of hypertriglyceridemia in HIV/AIDS patients: A meta-analysis

2017

Hypertriglyceridemia is common in antiretroviral therapy-treated patients and Omega 3 fatty acids are being used as a intervention in reducing serum triglycerides (TG) in these patients. The objective of this...

Exploring the views and experiences of HIV positive patients treated for cancer: A systematic review of the literature

2017

A systematic review of the literature was conducted to find out what is known about patients’ experiences of a dual diagnosis of HIV and cancer. We systematically searched the following...

Impact of highly active antiretroviral therapy on the prevalence of oral lesions in HIV-positive patients: A systematic review and meta-analysis

2017

The aim of this study was to determine whether highly active antiretroviral therapy (HAART) is associated with the prevalence of oral lesions in HIV-positive patients. This systematic review and meta-analysis...

Integrating cardiovascular diseases, hypertension, and diabetes with HIV services: A systematic review

2017

Non-communicable diseases (NCDs), including cardiovascular diseases (CVD), hypertension and diabetes together with HIV infection are among the major public health concerns worldwide. Health services for HIV and NCDs require health...

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