Category Archives: Epidemiology

The impact of HIV treatment as prevention in the presence of other prevention strategies: Lessons learned from a review of mathematical models set in resource-rich countries

2013

OBJECTIVE: We aimed to assess the potential prevention benefits of HIV treatment as prevention (TasP) in resource-rich countries and examine the potential interactions between TasP and other prevention strategies by...

Epidemiology of HIV infection in the Middle East and North Africa

2010

OBJECTIVE: The Middle East and North Africa (MENA) region continues to be perceived as a region with very limited HIV epidemiological data, raising many controversies about the status of the...

Uncovering the epidemic of HIV among men who have sex with men in Central Asia

2013

BACKGROUND: Research among people who inject drugs (PWID) in Central Asia has described same sex behavior among male PWID and may be associated with HIV and other infections. Little is...

The Indian pediatric HIV epidemic: A systematic review

2008

Despite an estimated 70,000 Indian children living with HIV infection, little is known about India’s pediatric HIV epidemic. Generalizations about epidemiology, natural history, and treatment outcomes from other resource-limited settings...

The utility of voluntary counselling and testing data as a source of information on HIV prevalence: A systematic review

2010

We explored the utility of routine HIV testing data from clinical services for estimating HIV prevalence. A systematic review identified 28 eligible publications, covering concentrated epidemics (16 of 28) and...

Systematic review of HIV and HCV infection among drug users in China

2009

To determine the HIV and hepatitis C virus (HCV) geographical distribution among drug users in China, a systematic literature review of 40 peer-reviewed publications (comprising 15,565 drug users) was conducted....

Therapeutic drug monitoring of antiretrovirals for people with HIV

2006

BACKGROUND: Despite the efficacy of combination antiretroviral therapy (ART) and the improvement in prognosis of those living with HIV/AIDS, a large proportion of individuals on ART does not achieve or...

Mathematical models for the study of HIV spread and control amongst men who have sex with men

2011

For a quarter of century, mathematical models have been used to study the spread and control of HIV amongst men who have sex with men (MSM). We searched MEDLINE and...

A decline in HIV and syphilis epidemics in Chinese female sex workers (2000-2011): A systematic review and meta-analysis

2013

BACKGROUND: Female sex workers (FSWs) play an important role in transmitting HIV and syphilis from high-risk groups to the general population. However, the trends in HIV and syphilis epidemics in...

Geographical representativeness of published and ongoing randomized controlled trials. The example of: Tobacco consumption and HIV infection

2011

Background: The challenge for evidence-based healthcare is to reduce mortality and the burden of diseases. This study aimed to compare where research is conducted to where research is needed for...

Assessing tuberculosis case fatality ratio: A meta-analysis

2011

BACKGROUND: Recently, the tuberculosis (TB) Task Force Impact Measurement acknowledged the need to review the assumptions underlying the TB mortality estimates published annually by the World Health Organization (WHO). TB...

HIV infection and sexual risk behaviour among youth who have experienced orphanhood: Systematic review and meta-analysis

2011

BACKGROUND: Previous research has suggested that orphaned children and adolescents might have elevated risk for HIV infection. We examined the state of evidence regarding the association between orphan status and...

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