Category Archives: Epidemiology
HIV, hepatitis B & C in people who inject drugs in India: A systematic review of regional heterogeneity & overview of opioid substitution treatment
BACKGROUND OBJECTIVES: This systematic review evaluates the human immunodeficiency virus (HIV), hepatitis C virus (HCV) and hepatitis B virus (HBV) burden among people who inject drugs (PWIDs) in India. In...
Brief interventions for alcohol misuse among people living with HIV: A meta-analysis
Background: One-third of people living with HIV (PLHIV) have alcohol misuse or alcohol use disorders which negatively affect course and outcome of HIV. Objectives: The meta-analysis sought to evaluate the effectiveness of...
Adherence, adverse drug reactions, and discontinuation associated with adverse drug reactions of HIV post-exposure prophylaxis: A meta-analysis based on cohort studies
Objective: Evaluate the profiles of post-exposure prophylaxis (PEP) adherence, adverse drug reactions (ADRs), and discontinuation associated with ADRs to provide information for further PEP program improvement and increase adherence to...
Risky sexual behaviour among HIV-infected adults in sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: Risky sexual behaviour raises serious public health concerns. The pooled prevalence of risky sexual behaviours among adults living with HIV/AIDS in sub-Saharan Africa was unknown. This systematic review determined...
Machine learning prediction models for clinical management of blood-borne viral infections: A systematic review of current applications and future impact
BACKGROUND: Machine learning (ML) prediction models to support clinical management of blood-borne viral infections are becoming increasingly abundant in medical literature, with a number of competing models being developed for...
Adherence to antiretroviral therapy among HIV patients in Ghana: A systematic review and meta-analysis
Maintaining a high level of adherence to antiretroviral therapy (ART) is critical to limiting rapid viral replication, drug resistance, and viral transmission. However, ART adherence remains a major challenge in...
Odds of HIV among incarcerated drug users: A systematic review and meta-analysis of Asian countries
Background: HIV makes up a large portion of infectious diseases globally. People injecting drugs in prisons are at high risk for contracting HIV infection. Prisons house ~10.2 million people globally,...
Virologic response to Dolutegravir plus Lamivudine in people with suppressed human immunodeficiency virus type 1 and historical M184V/I: A systematic literature review and meta-analysis
BACKGROUND: To investigate the impact of the M184V/I mutation on virologic response to dolutegravir plus lamivudine (DTG + 3TC) in suppressed-switch populations, a meta-analysis was performed using virologic outcomes from...
HPV infection profiles among people living with HIV and HPV vaccine acceptance among individuals with different HIV infection statuses in China: A systematic review and meta-analysis
To understand the HPV infection profiles among Chinese HIV/AIDS patients and the HPV vaccine acceptance among unvaccinated Chinese people with different HIV infection statuses after the HPV vaccine launch in...
A systematic review and meta-analysis of the global prevalence and determinants of COVID-19 vaccine acceptance and uptake in people living with HIV
People living with HIV (PLHIV) are at higher risk of poor outcomes of SARS-CoV-2 infection. Here we report the pooled prevalence of COVID-19 vaccine acceptance/uptake and determinants among this vulnerable...
HIV incidence among women engaging in sex work in sub-Saharan Africa: A systematic review and meta-analysis
INTRODUCTION: HIV incidence among women in sub-Saharan Africa (SSA) has declined steadily, but it is unknown whether new infections among women who engage in sex work (WESW) have declined at...
The impact of COVID-19 on HIV treatment of adolescents in sub-Saharan Africa: A scoping review
BACKGROUND: Adolescents living with HIV are a key population who are susceptible to poor health. The global coronavirus disease 2019 pandemic and widespread national COVID-19 restrictions has disrupted health service...
