Category Archives: Epidemiology
Burden of tuberculosis among vulnerable populations worldwide: An overview of systematic reviews
Background Tuberculosis is a communicable disease of public health concern that inequitably impacts the most vulnerable populations worldwide. Vulnerable populations are those with a high risk for tuberculosis disease and...
Fracture-related wound infections following surgical treatment of fractures in HIV-positive and HIV-negative patients: A meta-analysis
The meta-analysis aims to evaluate and compare fracture-associated wound infections (FAWIs) following surgical treatment of fractures in human immunodeficiency virus (HIV)-positive and HIV-negative patients. Examinations comparing HIV-negative to HIV-negative for...
Prevalence and impact of HIV infections in patients with rheumatic heart disease: A systematic review and meta-analysis
Socioeconomic factors such as poor health and poor nutrition in low- and middle-income countries (LMICs) may favour inflammatory reactions, thus contributing to the recurrence of rheumatic fever (RF) and thereby...
The incidence rate of tuberculosis and its associated factors among HIV-positive persons in Sub-Saharan Africa: A systematic review and meta-analysis
Background Tuberculosis, along with HIV, is the leading cause of mortality and morbidity globally. Despite the fact that several primary studies have been conducted on the incidence rate of tuberculosis...
The global prevalence of suicidal ideation and suicide attempts among men who have sex with men: A systematic review and meta-analysis
BACKGROUND: This study aimed to determine the global prevalence of suicidal ideation and attempts among men who have sex with men (MSM) as a systematic review, and meta-analysis. METHODS: For...
Collection of menopause data in studies of women living with HIV: A systematic literature review
Objectives An increasing number of women living with HIV are transitioning through midlife and menopause. Women living with HIV may experience earlier menopause and a higher symptom burden than women...
Effectiveness of linkae to care and prevention interventions following HIV self-testing: A global systematic review and meta-analysis
Over 38.4 million people were living with HIV globally in 2021. The HIV continuum includes HIV testing, diagnosis, linkage to combined antiretroviral therapy (cART), and retention in care. An important...
Prevalence and risk factors of tuberculosis among people living with HIV/AIDS in China: A systematic review and meta-analysis
OBJECTIVE: To estimate the prevalence and risk factors associated with tuberculosis (TB) among people living with human immunodeficiency virus (HIV) infection/acquired immunodeficiency syndrome (AIDS) in China. METHODS: A systematic review...
Fecal microbiota transplantation in human immunodeficiency virus-infected patient population: A systematic review and meta-analysis
BACKGROUND: Patients with human immunodeficiency virus (HIV) infection suffer from alterations in gut microbiota due to recurrent gastrointestinal infections and systemic inflammation. Fecal microbiota transplantation (FMT) appears to be a...
Prevalence and predictors of virological failure in pediatric patients on HAART in sub-Saharan Africa: A systematic review and meta-analysis
Antiretroviral treatment failure has emerged as a challenge in the management of pediatric human immunodeficiency virus (HIV) patients, especially in resource-limited countries despite accessibility to Highly Active Antiretroviral Therapy (HAART)....
Prevalence and trends of advanced HIV disease among antiretroviral therapy-naive and antiretroviral therapy-experienced patients in South Africa between 2010-2021: A systematic review and meta-analysis
BACKGROUND: Despite the significant progress made in South Africa in getting millions of individuals living with HIV into care, many patients still present or re-enter care with Advanced HIV Disease...
Immune reconstitution inflammatory syndrome, a controversial burden in the East African context: A systematic review and meta-analysis
Introduction It is well established that starting antiretroviral therapy (ART) increases a patient’s life expectancy among HIV-positive individuals. Considering the HIV pandemic, the major concern is initiation of ARTs to...
