Category Archives: Epidemiology
Adverse perinatal outcomes attributable to HIV in sub-Saharan Africa from 1990 to 2020: Systematic review and meta-analyses
Background: Maternal HIV infection and antiretroviral drugs (ARVs) are associated with increased risks of adverse perinatal outcomes. The vast majority of pregnant women living with HIV (WLHIV) reside in sub-Saharan Africa....
Safety and efficacy of long-acting injectable agents for HIV-1: Systematic review and meta-analysis
Background: HIV-1 infection continues to affect global health. Although antiretrovirals can reduce the viral load or prevent HIV-1 infection, current drugs require daily oral use with a high adherence level. Long-acting...
Post-exposure prophylaxis against blood-borne viral infections among health care workers: A bibliometric analysis
Background: Health care workers face a wide range of chemical, physical, and biological occupational hazards in their jobs. Objective: The present study aimed to investigate research trends on post-exposure prophylaxis (PEP) against...
A systematic review and meta-analysis of the prevalence of triplex infections (combined Human Immunodeficiency Virus, hepatitis B Virus, and hepatitis C Virus) among pregnant women in Nigeria
OBJECTIVE: We systematically identified the prevalence of triplex infections (combined human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV)) in pregnancy. METHODS: To gather information on...
Global and regional estimate of HIV-associated stroke burden: A meta-analysis and population attributable modeling study
Background: This study aimed to determine the correlation between human-immunodeficiency-virus (HIV) infection and stroke, as well as to estimate the global, regional, and national burden of HIV-associated stroke. Methods: A registered meta-analysis...
Characterizing blood pressure trajectories in people living with HIV following antiretroviral therapy: A systematic review
Objectives: The advent of antiretroviral therapy (ART) has reduced AIDS-related morbidity and mortality among people living with HIV (PLWH). Due to increased survival, PLWH have now been found to be at...
Prevalence of injecting drug use and HIV, hepatitis B, and hepatitis C in people who inject drugs in the Eastern Mediterranean region: A systematic review and meta-analysis
Background: Considerable disease burden is attributed to injecting drug use (IDU). This regional systematic review and meta-analysis aimed to assess the prevalence of IDU and the characteristics of people who inject...
Coronavirus (COVID-19) and sexualised drug use among men who have sex with men: A systematic review
Drug-related harms, including harms from sexualised drug use (SDU), are disproportionately experienced by sexual and gender minority people, relative to their majority counterparts. Chemsex, a type of SDU practiced mainly...
Preferences for oral- vs blood-based human immunodeficiency virus self-testing: A scoping review of the literature
BACKGROUND: The evidence on preferences for oral- vs blood-based human immunodeficiency virus self-testing (HIVST) has been heterogenous and inconclusive. In addition, most evaluations have relied on hypothetical or stated use...
Association of apolipoprotein E epsilon 4 and cognitive impairment in adults living with human immunodeficiency virus: A meta-analysis
Background: It is controversial whether the apolipoprotein E epsilon 4 allele (APOE ε4) is a risk gene for human immunodeficiency virus (HIV)-related neurocognitive impairment. This meta-analysis aimed to summarize evidence of...
Adult HIV-1 incidence across 15 high-burden countries in sub-Saharan Africa from 2015 to 2019: A pooled analysis of nationally representative data
Background Harmonised population-based surveys with recent HIV-1 infection testing algorithms permit pooled cross-sectional estimation of HIV incidence across multiple countries. We aimed to estimate adult HIV-1 incidence rates and number...
