Category Archives: Epidemiology

The demographic and socioeconomic correlates of behavior and HIV infection status across sub-Saharan Africa

2022

Background: Predisposition to become HIV positive (HIV + ) is influenced by a wide range of correlated economic, environmental, demographic, social, and behavioral factors. While evidence among a candidate handful have...

Determinants of voluntary counseling and testing service uptake among adult sub-Saharan Africans: A systematic review and meta-analysis

2022

Objective: To examine the major determinants of VCT service uptake among adults in SSA. Methods: Electronic databases were searched to identify eligible English language publications. Reporting of the study selection...

Incidence and mortality of non-AIDS-defining cancers among people living with HIV: A systematic review and meta-analysis

2022

Background: Non-AIDS-defining cancers (NADCs) are now becoming a rising cause of morbidity among people living with HIV (PLHIV) in the highly active antiretroviral therapy (HAART) era. We conducted a systematic review...

Suicidality among people living with HIV from 2010 to 2021: A systematic review and a meta-regression

2022

OBJECTIVE: The association between human immunodeficiency virus (HIV)/AIDS and suicidality is not well understood, partly because of variability in results. This meta-analysis aimed to investigate the predictive value of HIV/acquired...

Prevalence of cryptococcal meningitis among people living with human immuno-deficiency virus and predictors of mortality in adults on induction therapy in Africa: A systematic review and meta-analysis

2022

BACKGROUND: Cryptococcal meningitis (CM) is a leading cause of adult meningitis in countries with a high burden of HIV. It has remained a significant cause of morbidity and mortality in...

Comparing the effects of oral HIV self-testing with those of standard HIV testing for men who have sex with men (MSM): A systematic review and meta-analysis

2022

The WHO recommends HIV self-testing (HIVST) as an innovative strategy and an additional testing approach to attain UNAIDS targets to end HIV by 2030. HIVST is a process whereby a...

HIV prevalence ratio of international migrants compared to their native-born counterparts: A systematic review and meta-analysis

2022

Background: People on the move, including international migrants, may face health inequities that expose them to a higher risk for HIV than native-born populations. We conducted a systematic review to calculate...

Immunogenicity and safety of COVID-19 vaccines among people living with HIV: A systematic review and meta-analysis

2022

BACKGROUND: The immunogenicity and safety of COVID-19 vaccines among people living with human immunodeficiency virus (PLWH) are unclear. We aimed to evaluate the immunogenicity and safety of COVID-19 vaccines among...

Men who have sex with men is the high-risk drug resistance population: A meta-analysis of HIV-1 drug resistance profiles and trends in China

2022

WHAT IS KNOWN AND OBJECTIVE: Except for the transmitted drug resistance (TDR)’s standard sampling and monitoring protocol, China’s HIV-1 pretreatment drug resistance (PDR) and acquired drug resistance (ADR) results vary...

The clinical effect of point-of-care HIV diagnosis in infants: A systematic review and meta-analysis

2022

Background: Timely diagnosis and treatment of HIV is crucial in HIV-exposed infants to prevent the high rates of mortality seen during the first 2 years of life if HIV is untreated....

The global burden of cognitive impairment in people living with HIV: A systematic review and meta-analysis

2022

Objective: While life expectancies of people with HIV (PWH) have increased through the successes of antiretroviral treatment, cognitive impairment remains a pressing concern. Prevalence estimates vary worldwide as different definitions for...

Malaria prevalence in HIV-positive children, pregnant women, and adults: A systematic review and meta-analysis

2022

Background: Malaria in human immunodeficiency virus (HIV)-positive patients is an ever-increasing global burden for human health. The present meta-analysis summarizes published literature on the prevalence of malaria infection in HIV-positive children,...

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