Category Archives: Epidemiology
Non-invasive diagnosis of Pneumocystis jirovecii pneumonia: A systematic review and meta-analysis
BACKGROUND: Pneumocystis jirovecii pneumonia (PCP) is an opportunistic infection commonly affecting immunocompromised people. Diagnosis usually requires invasive techniques to obtain respiratory specimens. Minimally invasive detection tests have been proposed, but...
The prevalence, etiological agents, clinical features, treatment, and diagnosis of HIV-associated oral candidiasis in pediatrics across the world: A systematic review and meta-analysis
In HIV-infected pediatrics, oral candidiasis (OC) is a global issue of concern due to its association with dysphagia, malnutrition, and mortality. The present systematic review and meta-analysis are the first...
Outcomes of patients with HIV and COVID-19 co-infection: A systematic review and meta-analysis
Background Data on the association of human immunodeficiency virus (HIV) infection with adverse outcomes in patients with COVID-19 are conflicting. This systematic review and meta-analysis aimed to summarize the available...
Epigenome-wide epidemiologic studies of human immunodeficiency virus infection, treatment, and disease progression
Despite significant advances in the treatment and care of people with HIV (PWH), several challenges remain in our understanding of disease pathogenesis to improve patient care. HIV infection can modify...
Understanding the epidemiological HIV risk factors and underlying risk context for youth residing in or originating from the Middle East and North Africa (MENA) region: A scoping review of the literature
INTRODUCTION: HIV is the second leading cause of death among young people globally, and adolescents are the only group where HIV mortality is not declining. Middle East and North Africa...
Microbiota-meditated immunity abnormalities facilitate hepatitis B virus co-infection in people living with HIV: A review
Hepatitis B virus (HBV) co-infection is fairly common in people living with HIV (PLWH) and affects millions of people worldwide. Identical transmission routes and HIV-induced immune suppression have been assumed...
Curable sexually transmitted infections among women with HIV in sub-Saharan Africa: Systematic review and meta-analysis
OBJECTIVES: Sexually transmitted infections (STIs) cause significant morbidity among women with HIV and increase HIV transmission. We estimated the prevalence of four STIs among women with HIV in sub-Saharan Africa...
The prevalence, risk factors and outcomes of anaemia in South African pregnant women: A systematic review and meta-analysis
Background: Anaemia is associated with maternal and perinatal morbidity and mortality. The pooled prevalence of anaemia in the South African (SA) pregnant population was ascertained by systematically reviewing available literature....
