Category Archives: Determinants of Health
Meta-analysis: Implications of interleukin-28B polymorphisms in spontaneous and treatment-related clearance for patients with hepatitis C
BACKGROUND: Since 2009, several studies have identified single-nucleotide polymorphisms (SNPs) near the gene encoding for interleukin (IL)-28 (IL28B) that are strongly associated with spontaneous and treatment-induced hepatitis C virus (HCV)...
Emergence of drug resistance in HIV type 1-infected patients after receipt of first-line highly active antiretroviral therapy: A systematic review of clinical trials
Background. Resistance to antiretroviral combination therapy is associated with increased mortality. Understanding the relative risks of emerging resistance to first-line therapy is of importance for both resource-rich and resource-poor settings....
Contraception for the HIV-positive woman: A review of interactions between hormonal contraception and antiretroviral therapy
Background. Preventing unintended pregnancy in HIV-positive women can significantly reduce maternal-to-child HIV transmission as well as improve the woman’s overall health. Hormonal contraceptives are safe and effective means to avoid...
A meta-analysis of the relationship of child sexual abuse to HIV risk behavior among women
Objective: This study is a meta-analysis of the literature exploring the relationship between child sexual abuse (CSA) and HIV risk behavior among women. Four outcome variables were tested: unprotected sex;...
Does palliative care improve outcomes for patients with HIV/AIDS? A systematic review of the evidence
BACKGROUND: The need for palliative care in HIV management is underlined by the high prevalence of pain and symptoms, the toxicity, side effects, and virological failure associated with antiretroviral therapy,...
Effects of physician-nurse substitution on clinical parameters: A systematic review and meta-analysis
BACKGROUND: Physicians’ shortage in many countries and demands of high-quality and affordable care make physician-nurse substitution an appealing workforce strategy. The objective of this study is to conduct a systematic...
Use of hormonal contraceptives and HIV acquisition in women: A systematic review of the epidemiological evidence
Whether or not the use of hormonal contraception affects risk of HIV acquisition is an important question for public health. We did a systematic review, searching PubMed and Embase, aiming...
Partner notification uptake for sexually transmitted infections in China: A systematic literature review
Objective: China’s sexually transmitted infection (STI) epidemic requires comprehensive control programmes. Partner services are traditional pillars of STI control but have not been widely implemented in China. This study was...
The effects of housing status on health-related outcomes in people living with HIV: A systematic review of the literature
INTRODUCTION: HIV infection is increasingly characterized as a chronic condition that can be managed through adherence to a healthy lifestyle, complex drug regimens, and regular treatment and monitoring. The location,...
Impact of parental HIV/AIDS on children’s psychological well-being: A systematic review of global literature
This review examines the global literature regarding the impact of parental HIV/AIDS on children’s psychological well-being. Fifty one articles reporting quantitative data from a total of 30 studies were retrieved...
Systematic review exploring time trends in the association between educational attainment and risk of HIV infection in sub-Saharan Africa
OBJECTIVE: To assess the evidence that the association between educational attainment and risk of HIV infection is changing over time in sub-Saharan Africa. DESIGN AND METHODS: Systematic review of published...
